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Table 6 Correlations between miRNAs and biochemical markers

From: Expression and 7-day time course of circulating microRNAs in septic patients treated with nephrotoxic antibiotic agents

Group

Parameter

Spearman

r

hsa-miR-155-5p

hsa- miR-192-5p

hsa-miR-423-5p

Day 4

 Vancomycin

Screa

rs

0.786

–

–

 

P

0.048

–

–

NGAL

rs

0.821

–

–

 

P

0.034

–

–

 oATB

IL-6

rs

–

0.642

–

 

P

–

0.003

–

 all patients

NGAL

rs

0.351

0.339

0.419

 

P

0.017

0.021

0.004

IL-6

rs

0.328

–

–

 

P

0.026

–

–

Day 7

 Vancomycin

Screa

rs

–

0.821

–

 

P

–

0.034

–

NGAL

rs

–

0.929

–

 

P

–

0.007

–

PCT

rs

–

0.847

–

 

P

–

0.025

–

 oATB

PCT

rs

–

0.558

0.643

 

P

–

0.016

0.004

IL-6

rs

–

0.598

0.719

 

P

–

0.009

< 0.001

 all patients

PCT

rs

0.413

0.413

0.550

 

P

0.005

0.005

< 0.001

IL-6

rs

0.357

–

0.491

 

P

0.017

–

< 0.001

NGAL

rs

0.523

–

0,421

 

P

< 0.001

–

0.004

Screa

rs

0.419

–

0.313

 

P

0.004

–

0.036

  1. Abbreviations: IL-6 interleukin 6, NGAL neutrophil gelatinase–associated lipocalin, PCT procalcitonin, rs Spearman correlation coefficient r, Screa serum creatinine. P per Spearman correlation coefficient
  2. No correlation in gentamicin group was found - not shown