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Table 3 The comparison of clinical records among age groups

From: Study protocol and baseline characteristics of newly induced dialysis patients: a prospective multi-center cohort study with a biological sample bank, the Ibaraki Dialysis Initiation Cohort (iDIC) study

 

0–39 years old

40–64 years old

65–84 years old

over 85 years old

P

Number

16

188

304

34

 

Age (years old)

31.9 ± 7.3

55.4 ± 6.9

73.4 ± 5.9

87.3 ± 2.2

 

Gender (male/female)

12/4

133/55

203/101

16/18

0.51

Renal biopsy (%)

37.5

18.8

9.3

0.0

< 0.01

Medical checkup history (%)

66.7

57.0

29.8

12.5

< 0.01

Diabetes at dialysis initiation (%)

25.0

65.6

59.8

38.2

< 0.01

Hypertension at dialysis initiation (%)

93.8

97.3

93.7

88.2

0.12

Prior myocardial infarction (%)

0.0

8.1

12.1

8.8

0.28

Prior stroke (%)

0.0

12.1

18.4

8.8

0.06

Prior peripheral artery disease (%)

0.0

7.4

9.3

12.9

0.45

Prior malignancy (%)

0.0

7.3

18.7

11.8

< 0.01

Family history of kidney disease (%)

13.3

12.9

10.2

7.7

0.80

Primary kidney disease (%)

 Diabetic nephropathy

25.0

61.2

49.7

32.4

< 0.01

 Hypertensive nephrosclerosis

0.0

8.5

17.8

38.2

 Chronic glomerulonephritis

43.8

18.6

16.4

11.8

 Autosomal dominant polycystic kidney disease

0.0

5.3

1.3

0.0

 Rapidly progressive glomerulonephritis

0.0

1.6

3.0

5.9

 Other disease

25.0

2.7

6.9

8.8

 Unknown cause

6.3

2.1

4.9

2.9

Body mass index (kg/m2)

27.0 ± 9.4

25.9 ± 5.0

23.7 ± 3.7

22.3 ± 3.3

< 0.01

Systolic blood pressure (mmHg)

157.8 ± 29.9

154.1 ± 24.1

149.2 ± 26.5

141.4 ± 32.4

0.01

Diastolic blood pressure (mmHg)

99.1 ± 16.5

82.5 ± 16.3

75.0 ± 15.2

69.2 ± 14.1

< 0.01

Hemoglobin (g/dL)

10.0 ± 4.5

9.0 ± 1.6

8.9 ± 1.8

9.2 ± 1.7

0.53

Serum creatinine (mg/dL)

11.9 ± 3.7

10.2 ± 3.1

8.6 ± 2.6

7.2 ± 2.3

< 0.01

Estimated glomerular filtration rate (mL/min/1.73m2)

4.2 ± 1.3

4.9 ± 1.6

5.8 ± 1.8

6.7 ± 2.0

< 0.01

Serum uric acid (mg/dL)

9.4 ± 2.2

8.2 ± 2.2

7.8 ± 2.3

7.8 ± 2.4

0.03

Serum albumin (g/dL)

3.5 ± 0.7

3.3 ± 0.6

3.3 ± 0.6

3.1 ± 0.7

0.18

Serum total cholesterol (mg/dL)

192.2 ± 68.7

163.2 ± 52.8

154.3 ± 44.5

163.4 ± 47.1

0.08

Serum corrected calcium (mg/dL)

8.2 ± 1.1

8.3 ± 1.0

8.6 ± 1.1

8.8 ± 0.9

< 0.01

Serum phosphate (mg/dL)

6.8 ± 2.2

6.7 ± 2.0

6.1 ± 1.8

5.4 ± 1.4

< 0.01

Hemoglobin A1c (%)

5.4 ± 1.4

5.9 ± 0.9

5.9 ± 0.9

5.7 ± 0.7

0.04

Serum β2-microglobulin (mg/L)

17.8 ± 4.9

25.1 ± 43.2

29.0 ± 61.4

19.6 ± 7.1

0.07

Intact-parathyroid hormone (pg/ml)

494.3 ± 309.9

365.2 ± 286.4

241.7 ± 172.9

222.0 ± 58.9

< 0.01