Transcranial sonography depicts a larger substantia nigra echogenic area in renal transplant patients on calcineurin inhibitors than on rapamycin

Table 3 Correlations between TCS parameters (SN echogenic area and third ventricle width) and variables studied in controls and patient groups (RTRs – renal transplant patients; CNIs – calcineurin inhibitors; mTOR – rapamycin)

Variable	Controls		RTRs		CNIs		mTOR
Variable	SN	3rd V	SN	3rd V	SN	3rd V	SN	3rd V
Age
r	-0.050	0.657	0.174	0.606	0.291	0.581	-0.303	0.722
p	0.833	0.002	0.092	0.000	0.013	0.000	0.170	0.000
Serum creatinine
r	-0.085	0.441	0.001	-0.076	0.036	-0.083	0.360	0.016
p	0.828	0.235	0.991	0.537	0.798	0.553	0.206	0.958
Transplant duration
r	-	-	0.088	0.083	0.223	0.139	0.046	-0.107
p	-	-	0.394	0.425	0.058	0.240	0.838	0.635
Mesencephalon area
r	0.118	0.016	0.131	0.138	0.158	0.177	0.109	0.017
p	0.620	0.946	0.205	0.184	0.181	0.133	0.629	0.941
3^rd V
r	-0.063	-	0.001	-	0.031	-	-0.063	-
p	0.791	-	0.989	-	0.796	-	0.781	-
cIMT
r	-0.019	0.450	0.136	0.329	0.303	0.331	-0.368	0.317
p	0.937	0.046	0.189	0.001	0.009	0.004	0.092	0.150
MCA RI
r	0.247	-0.224	-0.033	0.407	0.019	0.372	-0.229	0.528
p	0.308	0.356	0.755	0.000	0.879	0.002	0.331	0.017
Kidney RI
r	0.084	0.150	0.020	0.418	0.053	0.356	-0.137	0.657
p	0.739	0.552	0.845	0.000	0.659	0.002	0.544	0.001
Spleen RI
r	-0.345	0.130	-0.011	0.502	-0.054	0.484	0.067	0.648
p	0.148	0.595	0.920	0.000	0.652	0.000	0.773	0.001
Spleen size
r	0.065	-0.375	0.291	-0.121	0.223	-0.087	0.347	-0.203
p	0.793	0.114	0.004	0.245	0.058	0.465	0.113	0.364

SN Substantia Nigra area, 3^rd V Third Ventricle width, BMI Body Mass Index, MCA Middle Cerebral Artery, RI Doppler Resistive Index, cIMT carotid Intima-Media Thickness

ISSN: 1471-2369