Fig. 1From: Phosphate restriction using a processed clay mineral reduces vascular pathologies and microalbuminuria in rats with chronic renal failurePhosphate levels of chronic renal failure rats (CRF) after 12 weeks of nephrectomy and phosphate and calcium enriched diet. A Serum phosphate was increased in untreated CRF rats whereas the serum phosphate level of phosphate adsorber treated CRF rats displayed control levels. B Excretion of phosphate during 24 h was decreased after 5/6 nephrectomy and even further after treatment with phosphate adsorbers. C Fecal phosphate concentrations were significantly decreased in nephrectomized rats compared to sham-operated rats. pClM treatment showed similar concentrations to untreated CRF rats. In contrast, LaC treatment resulted in significantly higher phosphate concentrations compared with untreated CRF and pClM-treated rats (min to max, #vs. sham, *vs. CRF, p ≤ 0.05; +pClM vs. LaC, p ≤ 0.05)Back to article page