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Fig. 4 | BMC Nephrology

Fig. 4

From: Phosphate restriction using a processed clay mineral reduces vascular pathologies and microalbuminuria in rats with chronic renal failure

Fig. 4

Reduction of fibrosis in coronary arteries of chronic renal failure rats (CRF) by pClM and LaC. A The perivascular collagen area (blue) to luminal area ratio of coronary arteries stained with Masson’s Goldner trichrome showed a perivascular fibrosis as consequence of 5/6 nephrectomy and a phosphate rich diet. Treatment with phosphate adsorber significantly prevented CRF rats from cardiovascular fibrosis. B The medial area to luminal area ratio indicates that adsorber treatment also prevented a swelling of the tunica media in coronary arteries (min to max, #vs. sham, *vs. CRF, p ≤ 0.05)

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