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Fig. 5 | BMC Nephrology

Fig. 5

From: Phosphate restriction using a processed clay mineral reduces vascular pathologies and microalbuminuria in rats with chronic renal failure

Fig. 5

Preservation of renal function in chronic renal failure rats (CRF) rats by pClM and LaC. A The processed clay mineral (pClM) and lanthanum carbonate (LaC) partially attenuated the progressing reduction of the GFR in nephrectomized rats. B The increase of uric acid in plasma due to 5/6 nephrectomy was significantly decreased by pClM and LaC treatment comparable to sham operated levels. C pClM significantly prevented microalbuminuria in CRF rats. D Phosphate and calcium enriched diet raised the mortality rates by 25% in untreated CRF rats. In contrast, all sham operated rats and rats which received pClM or LaC survived the investigation period until dissection after 12 weeks (min to max, #vs. sham, *vs. CRF, p ≤ 0.05)

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