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Table 2 Baseline biological parameters

From: Circulating Proprotein Convertase Subtilisin/Kexin type 9 level independently predicts incident cardiovascular events and all-cause mortality in hemodialysis black Africans patients

Variables

All

n = 207

Living

n = 116

Deceased

n = 91

p value

Glycemia fasting (mg/dL)

120.8 ± 49.4

112.3 ± 41,7

129.3 ± 56.1

0.337

Glycemia occasional (mg/dL)

126.4 ± 42.5

151.9 ± 41.7

113.6 ± 40.1

0.223

Hb (mg/dL)

8.6 ± 1.9

8.6 ± 1.8

8.5 ± 1.9

0.673

GB (/mm3)

6700.0

(4590.0–9000.0)

6580.0

(4550.0–9000.0)

6925.0

(4567.5–9050.0)

0.444

  N (%)

65.0 ± 13.3

63.7 ± 13.7

66.6 ± 12.7

0.192

  L (%)

24.9 ± 12.2

25.4 ± 11.6

24.4 ± 12.9

0.611

  M (%)

7.0 (4.0–10.0)

7.0 (3.0–10.0)

7.0 (4.0–10.0)

0.448

  B (%)

0.0 (0,0–0.05)

0.0 (0.0–0.08)

0.0 (0.0–1.0)

0.302

  E (%)

2.0 (1.0–3.0)

1.5 (1.0–3.0)

2.0 (1.0–2.5)

0.585

ESR (mm/1st h)

55.0 (20.0–112.0)

51.0 (20.0–77.0)

42.5 (28.5–85.0)

0.434

CRP (mg/dL)

24.0 (0.0–66.0)

24.0 (1.4–53.8)

36.0 (24.0–48.0)

0.177

S. Creatinin (mg/dL)

9.3 (4.0–16.3)

10.0 (7.5–12.4)

11.3 (6.3–16.3)

0.439

eGFR (ml/min/1.73m2)

8.3 (2.9–19.7)

5.9 (5.2–9.4)

7.0 (2.9–11.2)

0.260

Urea (mg/dL)

153.0 (28.2–386.3)

185.2 (112.4–255.3)

235.2 (84.0–386.3)

0.143

Uric Acid (mg/dL)

6.3 (2.7–8.0)

7.2 (5.7–10.2)

6.7 (5.9–8.0)

0.357

TC (mg/dL)

134.5(109.2–271.0)

134.5 (115.5–175.6)

206.3 (141.5–271.0)

0.166

HDLc (mg/dL)

39.1 (19.4–55.0)

39.1 (18.0–48.1)

53.1 (51.2–55.0)

0.854

LDLc (mg/dL)

172.8 (54.6–229.1)

137.0 (75.9–202.9)

127.6 (82.5–172.8)

0.482

TG (mg/dL)

130.4 (53.6–216.0)

103.9 (62.3–131.9)

132.2 (48.4–216.0)

0.897

Total Ca (mmol/L)

2.2 (0.9–2.5)

2.0 (1.7–2.3)

2.3 (5.1–2.5)

0.872

Ionized Ca (mmol/L)

0.87 (0.50–1.29)

0.87 (0.66–1.03)

1.1 (0.98–1.29)

0.557

K (mmol/L)

5.2 (4.2–7.4)

5.1 (4.5–5.8)

6.4 (5.3–7.4)

0.596

Na+ (mmol/L)

129.2 ± 9.9

129.7 ± 9.1

128.5 ± 11.1

0.586

Ph (mmol/L)

2.08 (1.83–2.81)

1.97 (1.67–2.55)

2.83 (1.83–2.95)

0.891

Intact PTH (pg/ml)

181.6 (107.0–192.3)

173.6 (86.7–192.3)

190.9 (101.0–192.3)

0.570

Vit D (ng/ml)

52.2 (43.8–63.5)

52.3 (41.1–65.4)

51.8 (36.0–65.7)

0.831

PCSK9 (ng/ml)

17.0 (12.5–20.4)

9.6 (8.6–11.6)

28.0 (24.0–31.0)

< 0.001

  Tertile 1 (< 9.58 ng/ml)

68(32.9)

58(50.0)

10(11.0)

 

  Tertile 2 (9.58–23.0 ng/ml)

75(36.2)

41(35.3)

34(37.4)

 

  Tertile 3 (> 23.0 ng/ml)

64(30.9)

17(14.7)

47(51.6)

 

Anti HVC Antibodies

9(5.2)

3(3.1)

6(8.0)

0.135

Hepatitis B surface antigen

6(3.5)

3(3.1)

3(4.0)

0.526

Anti HIV Antibodies

4(2.3)

1(1.0)

3(4.0)

0.217

  1. Data are expressed as mean ± standard deviation, absolute (n) proportions or relative frequency (%), median and interquartile (range). ESR erythrocyte sedimentation rate, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, MDRD GFR modification of diet in renal disease-glomerular filtration rate, PCSK9 Proprotein convertase subtilisin kexin type 9, TC Total cholesterol, TG triglycerides