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Table 5 Risk factors for death in the study population (Cox Regression Model and competitive risk)

From: Circulating Proprotein Convertase Subtilisin/Kexin type 9 level independently predicts incident cardiovascular events and all-cause mortality in hemodialysis black Africans patients

  

Univariate analysis

Cox Regression

Competitive Risk

Risk factors

cumulative incidence

of death

% (95% CI)

HR (95%CI)

P value

Adjusted HR

(95% CI)

P value

Adjusted HR

(95% CI)

p value

Stroke

  -No

0.53

(0.44–0.65)

1

 

1

 

1

 

  -Yes

0.88

(0.77–0.99)

3.59

(2,29-5,63)

< 0.001

2.50

(1.56–4.00)

< 0.001

1.67

(1.06–2.67)

0.001

S. Albumin (g/dL)

  ≥ 3.5

0.35

(0.30–0.41)

1

 

1

 

1

 

  < 3.5

0.65

(0.61–0.76)

2.96

(1.86–4.73)

< 0.001

2.07

(1.28–3.35)

0.030

1.76

(1.06–2.91)

0.027

PCSK 9

  -Tertile 1

0.15

(0.08–0.26)

1

 

1

 

1

 

  -Tertile 2

0.59

(0.46–0.76)

4.06

(2.00–8.26)

< 0.001

3.20

(1.58–6.50)

0.001

3.93

(2.63–5.23)

< 0.001

  -Tertile 3

0.97

(0.94–1.00)

8.33

(4.16–16.72)

< 0.001

5.72

(2.88–11.35)

< 0.001

6.47

(5.19–7.75)

< 0.001

  1. CI Confidence Intervalle, PCSK9 Proprotein convertase subtilisin kexin type 9, HR Hazard ratios