Fig. 2

Physical functional assessed 3-months after hospital discharge in survivors of critical illness grouped by severity of acute kidney injury during index ICU admission. Group A = patients with AKI stage 1 or no AKI; Group B = patients with AKI stage 2 or 3 that did not require RRT; Group C = patients with AKI stage 3 that required acute RRT. Panel A: Patients that required RRT in the ICU ambulated the shortest distances during six-minute walk test, but this was not statistically different between the three groups (p = 0.113). Predicted* represents the distance patients were estimated to achieve based on age, sex, and height. Patients with AKI stage 2 or 3 achieved 38% [IQR: 29 – 56] of their predicted distances compared to 58% [IQR: 34 – 78] in patients with AKI stage 1 or no AKI (p = 0.041). Panel B: Patients with AKI stage 2 or 3, and especially those that required acute RRT in the ICU had slower 4-m habitual gait speeds when compared to patients with AKI stage 1 or no AKI (p for 3-group comparison = 0.031). AKI = acute kidney injury; RRT = renal replacement therapy