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Table 1 Basic characteristics stratified by DM and uric acid level

From: Hyperuricemia and diabetes mellitus when occurred together have higher risks than alone on all-cause mortality and end-stage renal disease in patients with chronic kidney disease

  

DM

No DM

Variable

Overall (N = 4380)

UA > 7 (n = 1174)

UA < 7 (n = 602)

p-value

UA > 7 (n = 1737)

UA < 7 (n = 867)

p-value

Age (y)

71 ± 14.8

71 ± 12.2

73 ± 11.8

0.001a

70 ± 16.8

72 ± 15.3

< 0.001a

Male sex

2747(62.7)

741(63.1)

352(58.5)

0.057b

1142(65.7)

512(59.1)

< 0.001b

CKD stage

   

< 0.001b

  

< 0.001b

  3

2076(47.4)

461(39.3)

323(53.7)

 

803(46.2)

489(56.4)

 

  4

1364(31.1)

414(35.3)

200(33.2)

 

530(30.5)

220(25.4)

 

  5

940(21.5)

299(25.5)

79(13.1)

 

404(23.3)

158(18.2)

 

Ever smoke

1688(38.5)

509(43.4)

213(35.4)

0.001b

670(38.6)

296(34.1)

0.027b

Previous CAD

225(5.1)

86(7.3)

31(5.1)

0.08b

69(4.0)

39(4.5)

0.526b

Baseline SBP (mmHg)

134 ± 18.7

138 ± 19.5

135 ± 18.1

0.013a

133 ± 18.5

132 ± 17.9

0.40a

1 year mean SBP (mmHg)

134 ± 16.1

137 ± 16.4

135 ± 15.6

0.014a

133 ± 16.1

131 ± 15.3

0.118a

Baseline DBP (mmHg)

75 ± 11.1

75 ± 10.8

74 ± 10.3

0.043a

75 ± 11.4

75 ± 11.2

0.34a

1 year mean DBP (mmHg)

74 ± 9.5

75 ± 8.9

74 ± 8.9

0.116a

75 ± 10.0

74 ± 9.4

0.092a

Baseline UA (mg/dl)

8.1 ± 2.5

9.2 ± 3.1

6.0 ± 1.1

< 0.001a

9.1 ± 1.8

6.0 ± 1.1

< 0.001a

1 year mean UA (mg/dl)

8.0 ± 2.1

9.1 ± 2.1

5.9 ± 0.9

< 0.001a

8.9 ± 1.5

5.9 ± 0.9

< 0.001a

Baseline cholesterol (mmol/l)

185.2 ± 51.4

183.5 ± 53.0

180.1 ± 50.8

0.214a

187.9 ± 50.1

185.7 ± 51.9

0.325a

Statin usage

1522(34.7)

544(46.3)

279(46.3)

0.997b

473(27.2)

226(26.1)

0.528b

ACEi/ARB usage

2540(58.0)

802(68.3)

401(66.6)

0.468b

916(52.7)

421(48.6)

0.045b

Uric acid-lowering drugs

1228 (28.0)

306 (26.1)

107 (17.8)

< 0.0001

599 (34.5)

216 (24.9)

< 0.0001

  1. Continuous variables are expressed as mean ± SD
  2. Categorical data are presented as numbers (percentages). aIndependent T-Test. bChi-Square Test