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Table 3 Renal histopathology in MPA patients with or without RA

From: Anti-neutrophil cytoplasmic antibody associated vasculitis in patients with rheumatoid arthritis

 

With RA(n = 9)

Without RAa(n = 36)

P

Percentage of normal glomeruli

24.3 ± 10.8%

27.9 ± 22.7%

.64

Percentage of cellular crescent glomeruli

23.1 ± 18.7%

34.0 ± 18.4%

.10

Percentage of global sclerotic glomeruli

37.0 ± 23.5%

26.9 ± 24.0%

.26

Tubulointerstitial chronic index

1.9 ± 0.9

1.6 ± 0.9

.46

Histopathological classificationb

 Focal class

1 (11.1%)

7 (19.4%)

.51

 Crescent class

1 (11.1%)

9 (25.0%)

 Mixed class

3 (33.3%)

13 (36.1%)

 Sclerotic class

4(44.4%)

7 (19.4%)

  1. aRenal-biopsied patients with both MPA and RA in our center were 1:4 matched with patients with isolated MPA adjusted by sex and age
  2. bANCA-associated glomerulonephritis was classified according to the histopathological classification proposed in 2010 [7]