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Table 3 Detailed characteristics of the autoimmune disease group

From: SARS-COV-2 vaccine responses in renal patient populations

 

N = 223

Diagnosis (Number (%))

 - ANCA-associated vasculitis

133 (60)

 - Large vessel vasculitis

11 (5)

 - Systemic lupus erythematosus

27 (12)

 - Behcet’s disease

17 (8)

 - Othera

25 (16)

GFR (ml/min/m2) (median (IQR))

84 (56–90)

Rituximab (Number (%))

 - Received within 6 months

70 (31)

 - Received within 12 months

108 (48)

 - Received within 5 years

128 (57)

Days since last rituximab dose (median (IQR)

162 (110–275)

IV cyclophosphamide (Number (%))

 - Received within 6 months

76 (34)

 - Received within 12 months

103 (46)

Days since last IV cyclophosphamide dose (median (IQR))

79 (19–177)

Other concurrent immunosuppressive agents (Number (%))

 - Mycophenolate mofetil

33 (15)

 - Azathioprine

17 (8)

 - Methotrexate

13 (6)

 - Anti-TNF alpha therapy

9 (4)

 - Belimumab

11 (5)

 - Tocilizumab

4 (2)

Concurrent prednisolone (Number (%))

111 (50)

- Total daily dose (mg) (median (IQR))

2 (0–5)

  1. Autoimmune disease patients were included from Cambridge (n = 213) and Leicester (n = 10). Data are reported at the time of most recent sampling. aOther includes polyarteritis nodosa, IgG4 disease, IgA vasculitis, glomerulonephritis including focal segmental glomerulonephritis (FSGS) and membranous nephropathy