Table 1 Comparison of baseline characteristics between patients with and without nephrotic syndrome before matching in IgA nephropathy
Variables | NS group (n = 59) | non-NS group (n = 954) | P Value |
|---|---|---|---|
Age (y) | 42.69 ± 14.96 | 37.78 ± 12.17 | 0.003 |
Gender (M/F) | 26/33 | 450/504 | 0.643 |
SBP (mm Hg) | 124 ± 14 | 125 ± 13 | 0.84 |
HB (g/l) | 120.69 ± 24.73 | 130.24 ± 21.48 | < 0.001 |
Scr (umol/l) | 127.34 ± 114.88 | 90.89 ± 55.48 | < 0.001 |
eGFR (ml/min.1.73m2) | 68.52 ± 33.04 | 93.11 ± 31.08 | < 0.001 |
Proteinuria (g/24 h, median,IQR) | 5160 (4100 ~ 6444) | 1134 (602 ~ 2106) | < 0.001 |
Uric acid (umol/L) | 400.52 ± 107.04 | 361.40 ± 106.45 | 0.008 |
Total IgA (mg/ml) | 295.62 ± 111.48 | 324.71 ± 138.15 | 0.127 |
Alb (g/l) | 24.8 ± 3.98 | 38.99 ± 7.98 | < 0.001 |
C3 (mg/dl) | 92.88 ± 27.70 | 95.97 ± 44.20 | 0.597 |
C4 (mg/dl) | 25.16 ± 8.98 | 26.58 ± 7.48 | 0.475 |
Urine RBC (/ul,median,IQR) | 84 (13 ~ 205) | 12 (5 ~ 34.52) | < 0.001 |
M (M0/M1) | 5/54 | 28/926 | 0.186 |
E (E0/E1) | 14/45 | 627/327 | < 0.001 |
S (S0/S1) | 14/45 | 337/617 | 0.293 |
T (T0/T1/T2) | 8/29/22 | 360/399/195 | < 0.001 |
C (C0/C1/C2) | 8/20/31 | 356/485/113 | < 0.001 |