Table 1 Study procedures flowchart

 Eligibility screen

X

 Contact information

X

 Informed consent

X

 FMD

X

X

X

X

 Arterial stiffness

X

X

X

X

 Assessment of intima media thickness

X

X

X

X

 Echocardiography

X

X

X

X

 LUS

X

X

X

X

 BIS

X

X

X

X

 Blood collection

X

X

X

X

 Clinical data

X

X

X

X

X

 IL1, IL6, VCAM-1, endoglin, NO and ADMA

X

X

X

X

 CV risk

X

X

X

 Mortality rate

X

 Renal outcome

X

X

X

 ED

X