Groups | Pathologic Diagnosis | Cases | Light Microscopy Pattern | Location of Deposits by EM | Clinical Presentation | Literature |
---|---|---|---|---|---|---|
Ā | Idiopathic | |||||
1 | Minimal change | 1 | Minimal lesion pattern | mes and subendo | normal urinalysis (donor kidney at 0āhour biopsy) | #26 |
2 | Ā | NA | NS | #25 | ||
1 | Ā | mes | NS | #27 | ||
2 | Mesangial proliferative GN | 1 | Mesangial proliferative pattern | NA | SubNS, hematuria | #25 |
1 | Ā | NA | NS and nephritic | #28 | ||
1 | Ā | mes | SubNS | #24 | ||
3 | Focal proliferative GN | 5 | Focal proliferative pattern | 2 subepi; 1 TM and subepi; 2 NA | NS; or NS and hematuria | #25 |
2 | Ā | mes, subendo, subepi | NS | #23 | ||
4 | Diffuse proliferative GN | 2 | Diffuse proliferative pattern | NA | RPGN, NS, malignant HTN | #25 |
1 | Ā | NA | SubNS, hypertension | #29 | ||
7 | Ā | NA | NS; or subNS; or NS and nephritic; or RPGN | #28 | ||
10 | Ā | NA | NS; or nephritic; or NS and nephritic; or CRF | #30 | ||
7 | Ā | mes, subendo, subepi | NS or subNS, hematuria, renal insufficiency | #23 | ||
5 | Diffuse proliferative GN with crescents | 2 | Diffuse proliferative with crescents | mes, subendo, subepi; subepi | RPGN, subNS, hematuria, malignant HTN | #25 |
10 | Ā | NA | NA | #30 | ||
2 | Ā | mes, subendo, subepi | SubNS and hematuria | #22 | ||
1 | Ā | mes, subendo, subepi | SubNS, hematuria and renal insufficiency | #23 | ||
6 | MPGN | 1 | Membranoproliferative pattern | mes, subendo, subepi | NS | #25 |
2 | Ā | NA | NS and nephritic | #28 | ||
3 | Ā | mes and subendo | RPGN; chronic renal failure;or NS | #24 | ||
1 | Ā | NA | NS and nephritic | #29 | ||
12 | Ā | NA | RPGN; or NS; or NS and nephritic | #30 | ||
1 | Ā | mes, subendo, subepi | NS, hemturia | #22 | ||
3 | Ā | mes, subendo, subepi | NS, hematuria | #23 | ||
7 | MN | 1 | Membranous pattern | NA | NS, renal insufficiency | #29 |
2 | Ā | NA | 1 NS; 1 NS and nephritic | #28 | ||
10 | Ā | subepi | NS; or subNS | #24 | ||
21 | Ā | NA | NS; or subNS with nephritic | #30 | ||
4 | Ā | mes, subendo, subepi | NS or subNS | #23 | ||
8 | Diffuse proliferative GN with MN | 1 | Diffuse proliferative and membranous patterns | mes, subendo, subepi | NS, hematuria, renal insufficiency | #22 |
9 | FSGS | 2 | Segmental chronic lesions | 1 mes, subendo, subepi; 1 NA | NS | #25 |
10 | FSGS with TMA | 1 | Segmental chronic lesions and TMA | NA | NS | #25 |
11 | C1q nephropathy | 1 | Diffuse proliferative pattern | mes and subendo | NS | #24 |
3 | Proliferative GN in 1; minima change in 2 | NA | NA | #30 | ||
12 | IgA nephropathy | 1 | Segmental chronic lesions | NA | SubNS and hematuria | #25 |
3 | Focal mesangial proliferative pattern | mes | NS; SubNS; or chronic renal failure | #24 | ||
16 | Mesangial proliferative pattern | NA | NA | #30 | ||
13 | IgA nephropathy with crescents | 3 | Focal or diffuse proliferative pattern with crescents | 1 subendo; 2 NA | SubNS, hematuria, RPGN, malignant HTN | #25 |
2 | Focal or diffuse proliferative patternĀ with crescents | mes | RPGN | #24 | ||
Ā | Secondary | |||||
14 | Infection-related GN | 1 | Minimal lesionĀ pattern | mes and subendo | Microalbuminemia, hematuria | #25 |
1 | Diffuse proliferative pattern | mes, subendo, TM, subepi humps | RPGN | #25 | ||
15 | Infecious endocarditis-related GN | 1 | Diffuse proliferative pattern | subepithelial humps | MSSA infectious endocarditis | #24 |
16 | Post-streptocococal GN | 2 | Diffuse proliferative pattern | subepithelial humps | Nephritic; or NS | #24 |
17 | IgA-dominant infection-related GN | 2 | Diffuse mesangial proliferative pattern | NA | NA | #30 |
1 | Diffuse proliferative pattern | subepithelial humps | Nephritic | #24 | ||
18 | HBV-associated MN | 1 | Membranous pattern | subepi | NS | #24 |
1 | Membranous pattern | NA | NS | #30 | ||
19 | HIV-associated immune complex GN (6 cases with concurrent HCV infection) | 6 | Focal proliferative pattern | mes, subendo, subepi | NS or subNS, hematuria, renal insufficiency, 1 HCV+ | #31 |
7 | Diffuse proliferative pattern | mes, subendo, subepi | NS or subNS, hematuria, renal insufficiency, 4 HCV+ | #31 | ||
1 | Membranous pattern | subepi, TM, subendo, mes | NS, HCV+ | #31 | ||
20 | ANCA-associated GN | 2 | Diffuse proliferative patternĀ with crescents | NA | RPGN; or subNS and hematuria | #25 |
1 | Membranoproliferative patternĀ with crescents | NA | RPGN, HTN crisis, p-ANCA positive | #32 | ||
21 | Amyloidosis | 7 | Amyloid protein deposition | NA | NA | #30 |
22 | Cancer-associated MN | 3 | Membranous, anti-PLA2R negative | 1 mes, subepi; 2 subepi | NS; or subNS and hematuria; all with cancer | #25 |
23 | Glomerular disease in IPEX patient | 1 | Membranous with focal proliferative pattern | mes, subendo, subepi | NS, hematuria | #33 |