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Table 3 Clinical information of patients presenting with rapidly decline renal function/AKI

From: Managing acute presentations of atheromatous renal artery stenosis

 

Presentation

Co-morbidities

Clinical Features

Anatomy

Intervention

Outcome

1

56 yr female referred from another unit with AKI, volume overload and htn

Diastolic dysfunction

HTN ( 4 agents)

PVD with claudication distance of < 20 m

CKD (eGFR 29 ml/min)

Smoker

BP: 189/90 mmHg

Creatinine: 1017 µmol/L (AKI on CKD) with hyperkalaemia and metabolic acidosis

MRA

Rt: 100% (8.5 cm)

L: > 80% (10.5 cm)

LPTRAS

Immediate ↑ in UO (1.5L/24 h) and ↓ creatinine to 598 µmol/L

1 month:

Creat 115 µmol(eGFR: 44 ml/min)

BP: 149/70 mmHg on 2 agents

RIP 7 years later: no further presentations

4

78 yr female transferred from another institution to our unit with accelerated phase hypertension, deteriorating renal function and pulmonary oedema

HTN with LVH

NIDDM

CKD (eGFR 40 ml/min)

History of temporal arteritis

PVD

Diverticular disease

Renal adenocarcinoma requiring L nephrectomy

Bp: 157/80 mmHg on iv diuretic infusion and 4 agents

Volume overloaded

Creatinine: 519 µmol/l (eGFR: 7 ml/min)

MRA

Rt: > 90% (11 cm)

Rt PTRA

Within 1 week:

BP < 130/80 mmHg on 2 agents

Independent of RRT with creatinine of 128 µmol/L

5

63 yr male transferred for AKI on CKD

CKD 3 (ARVD within previous L PTRAS in 2012)

HTN

Previous ischaemic stroke

NIDDM

Hyperthyroidism treated with radioactive iodine therapy

Smoker

BP: 198/92 mmHg on 3 agents

Creatinine: 319 µmol/L(eGFR: 9 ml/min)

uPCR: 800 mg/mol

Formal Angiogram:

Occluded L stent

L PTRAS

(Fig. 2)

Within 1 month:

BP: < 130/80 mmHg on no agents

Creatinine:240 µmol/L (eGFR: 24 ml/min)

uPCR: 132 mg/mol

9

74 yr female presented acutely with anuric AKI

HTN

IHD with angina

Macular degeneration

Smoker

BP 190/90 mmHg

Volume overloaded

Creatinine: 633 µmol/L (eGFR: 6 ml/min)

Renal US:

Rt: 11 cm

L: 8.2 cm

Formal Angiogram:

Rt: > 70%

L: 100%

Rt PTRAS

Within 1 month:

BP: < 130/80 mmHg on single agent

Creatinine: 150 µmol/L (eGFR: 31 ml/min)

  1. AKI Acute Kidney Injury, HTN hypertension, PVD peripheral vascular disease, CKD chronic kidney disease, eGFR estimated glomerular filtration rate, BP blood pressure, MRA Magnetic Resonance Angiography, L left, PTRAS percutaneous transluminal renal angioplasty with stenting, UO urinary output, LVH left ventricular hypertrophy, NIDDM non insulin dependent diabetes mellitus, PTRA percutaneous transluminal renal angioplasty, RRT renal replacement therapy, ARVD atheromatous renovascular disease, uPCR urine protein to creatinine ratio, IHD ischaemic heart disease, US ultrasound, Rt right