Skip to main content

Table 1 Baseline characteristics of patients in the study group

From: Effectiveness and safety of KunXian capsule for the treatment of IgA nephropathy

Characteristic

Baseline

(n = 55)

At First Visit

(n = 55)

P-value

Age (years)

 Female sex, n (%)

24 (43.6%)

 

 Diabetes mellitus

4 (7.3%)

  

 Previous immunosuppressants

48 (87.3%)

 

 Receiving immunosuppressants at baselinea

36 (65.5%)

  

 Receiving TW at baselinea

20 (36.4%)

 

 Receiving RASi at baseline

50 (90.9%)

 

 Proteinuria (g/24 h)

2.2 (1.5–3.2)

0.94 (0.61–1.65)

< 0.001

 Mean artery pressure (MAP, mmHg)

94.4 ± 10.6

89.1 ± 10.9

< 0.001

 Estimated GFR (ml/min per 1.73 m2)

65 ± 13

65 ± 14

0.71

 Estimated GFR < 60 ml/min per 1.73 m2

21 (38.2%)

21 (38.2%)

 

 Serum albumin (g/dl)

4.05 ± 0.35

3.66 ± 0.42

< 0.001

 Total cholesterol (mg/dL)

216.6 ± 46.4

247.5 ± 50.3

< 0.001

 Triglyceride ((mg/dL)

168.3 ± 79.7

141.7 ± 70.9

0.06

 LDL cholesterol (mg/dL)

119.9 ± 34.8

147.0 ± 46.4

< 0.001

 HDL cholesterol (mg/dl)

46.4 ± 11.6

61.9 ± 15.5

< 0.001

 White blood cell count (WBC, 10^9/L)

6.9 ± 2.4

6.1 ± 2.1

0.006

 Alanine aminotransferase (ALT, U/L)

24 (14–37)

27 (21–49)

< 0.001

 Aspartate aminotransferase (AST, U/L)

23 (20–29)

27 (23–32)

< 0.001

  1. TW tripterygium Wilfordii multiglycoside (the second generation of TwHF preparations), RASi Renin-angiotensin system inhibitors; a TW is also considered as an immunosuppressant