From: Effectiveness and safety of KunXian capsule for the treatment of IgA nephropathy
Characteristic | Baseline (n = 55) | At First Visit (n = 55) | P-value |
---|---|---|---|
Age (years) | |||
Female sex, n (%) | 24 (43.6%) | – | |
Diabetes mellitus | 4 (7.3%) | ||
Previous immunosuppressants | 48 (87.3%) | – | |
Receiving immunosuppressants at baselinea | 36 (65.5%) | ||
Receiving TW at baselinea | 20 (36.4%) | – | |
Receiving RASi at baseline | 50 (90.9%) | – | |
Proteinuria (g/24 h) | 2.2 (1.5–3.2) | 0.94 (0.61–1.65) | < 0.001 |
Mean artery pressure (MAP, mmHg) | 94.4 ± 10.6 | 89.1 ± 10.9 | < 0.001 |
Estimated GFR (ml/min per 1.73 m2) | 65 ± 13 | 65 ± 14 | 0.71 |
Estimated GFR < 60 ml/min per 1.73 m2 | 21 (38.2%) | 21 (38.2%) | |
Serum albumin (g/dl) | 4.05 ± 0.35 | 3.66 ± 0.42 | < 0.001 |
Total cholesterol (mg/dL) | 216.6 ± 46.4 | 247.5 ± 50.3 | < 0.001 |
Triglyceride ((mg/dL) | 168.3 ± 79.7 | 141.7 ± 70.9 | 0.06 |
LDL cholesterol (mg/dL) | 119.9 ± 34.8 | 147.0 ± 46.4 | < 0.001 |
HDL cholesterol (mg/dl) | 46.4 ± 11.6 | 61.9 ± 15.5 | < 0.001 |
White blood cell count (WBC, 10^9/L) | 6.9 ± 2.4 | 6.1 ± 2.1 | 0.006 |
Alanine aminotransferase (ALT, U/L) | 24 (14–37) | 27 (21–49) | < 0.001 |
Aspartate aminotransferase (AST, U/L) | 23 (20–29) | 27 (23–32) | < 0.001 |