Skip to main content

Table 3 Factors associated for Complete/Partial or Complete remission after KunXian treatment in patients with IgA Nephropathy (n = 55)

From: Effectiveness and safety of KunXian capsule for the treatment of IgA nephropathy

Factor a

Complete or Partial remission

Complete remission

HR

95% CI

P value

HR

95% CI

P value

Sex (Female)

3.67

1.63–8.27

0.001

3.62

1.39–9.42

0.008

Age at baseline (For every 10 years old)

0.98

0.93–1.03

0.41

1.01

0.95–1.07

0.68

Proteinuria at baseline (g/24 h) b

0.17

0.04–0.85

0.03

0.02

0.002–0.29

0.003

eGFR at baseline (For every 10 ml/min per 1.73 m2)

0.92

0.66–1.29

0.64

1.49

0.88–2.55

0.14

Mean artery pressure at baseline (For every 10 mmHg)

1.03

0.97–1.55

0.88

0.85

0.49–1.48

0.57

Switching from TW

0.22

0.08–0.55

0.001

0.15

0.04–0.57

0.005

KX Dosage (For every 20μg per capsule)

1.33

0.93–1.91

0.12

2.62

1.47–4.69

0.001

  1. HR hazard rate of complete or partial remission, eGFR estimated glomerular filtration rate, TW tripterygium Wilfordii multiglycoside (the second generation of TwHF preparations), KX KunXian capsule
  2. a Multivariable Cox proportional hazards models were used; b Proteinuria was square root-transformed before statistical analyses