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Table 2 Univariate and multivariate analysis to determine risk factors of postoperative AKI after abdominal surgery

From: Risk factors for acute kidney injury after major abdominal surgery in the elderly aged 75 years and above

 

Univariate analysis

Multivariate analysis

Unadjusted OR (95% CI)

P

Adjusted OR (95% CI)

P

Male

0.444 (0.211–0.934)

0.032

  

Ages

1.129 (1.048–1.216)

0.001

1.112 (1.020–1.212)

0.016

Body mass index

0.969 (0.878–1.070)

0.537

  

Hypertension

0.798 (0.392–1.627)

0.535

  

Diabetes mellitus

0.535 (0.582–2.837)

0.535

  

Ischemic heart diseases

1.120 (0.493–2.547)

0.787

  

Congestive heart diseases

1.871 (0.415–8.428)

0.734

  

Cerebrovascular diseases

0.858 (0.323–2.281)

0.759

  

COPD

3.419 (0.718–16.285)

0.311

  

Solid malignancy

0.711 (0.338–1.495)

0.366

  

Serum hemoglobin

0.988 (0.969–1.006)

0.193

  

Serum albumin

0.863 (0.802–0.929)

 < 0.001

0.900 (0.829–0.977)

0.012

Alanine aminotransferase

1.004 (1.001–1.007)

0.024

  

Aspartate aminotransferase

1.003 (1.000–1.005)

0.037

  

Baseline eGFR (mL/min/1.73 m2) < 60

6.544 (3.137–13.649)

 < 0.001

3.401 (1.479–7.820)

0.004

ASA score

3.063 (1.584–5.923)

0.001

  

Charlson score

1.203 (1.035–1.399)

0.071

  

RCRI score

1.895 (1.204–2.981)

0.005

  

Non-renal RCRI score

1.654 (1.034–2.645)

0.033

  

Surgical approach(Laparoscopic)

0.623 (0.294–1.319)

0.213

  

Intraoperative characteristics

 Duration of anesthesia

1.000 (0.997–1.003)

0.850

  

 Operative time

1.000 (0.996–1.003)

0.933

  

 IOH

4.141 (2.023–8.477)

 < 0.001

3.509 (1.553–7.929)

0.003

 Amount of crystalloids use

1.000 (0.999–1.001)

0.476

  

 Blood loss

0.999 (0.995–1.002)

0.465

  

 Vasoactive drug use

0.783 (0.330–1.857)

0.578

  

 Usage of nephrotoxic drugs

  Hydroxyethyl starch

0.292 (0.111–0.768)

0.008

  

  NSAID

0.413 (0.097–1.761)

0.333

  

  Hydroxyethyl starch + NSAID

2.896 (1.375–6.098)

0.004

3.596 (1.559–8.292)

0.003

  Hydroxyethyl starch + furosemide

11.875 (3.648–38.654)

 < 0.001

5.724 (1.476–22.199)

0.012

  1. COPD Chronic obstructive pulmonary disease, eGFR estimated glomerular filtration rate, ASA American Society of Anesthesiologists, RCRI Revised Cardiac Risk Index, IOH intraoperative occurrence of hypotension, NSAIDs nonsteroidal anti-inflammatory drugs, OR odds ratio, CI confidence interval
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BMC Nephrology

ISSN: 1471-2369

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