Table 1 Baseline characteristics of the HD cohort stratified by outcome

Clinical characteristics

 Age(years)

56(46,65)

64(52,77)

54(44,64)

0.010^*

 Gender(male/female)

62(57.4%) / 46(42.6%)

9(52.9%) / 8(47.1%)

53(58.2%) / 38(41.8%)

0.685

 HD duration(months)

60(29,122)

74(34,155)

58(27,113)

0.299

 Follow-up time(months)

52(39,52)

37(16,41)

52(52,52)

 < 0.001^*

 mCCI

3(2,4)

5(2,5)

3(2,4)

0.060

 SBP(mm Hg)

152 ± 22

142 ± 26

154 ± 20

0.037^*

 DBP(mm Hg)

77 ± 15

72 ± 18

79 ± 14

0.080

 MAP(mm Hg)

101 ± 18

95 ± 19

104 ± 13

0.097

 PP(mm Hg)

74 ± 21

70 ± 18

75 ± 21

0.367

 Hemoglobin(g/L)

112.80(105.35,118.00)

107.39(102.55,119.95)

113.00(106.67,117.6)

0.236

 WBC(× 10^9/L)

6.16(5.18,7.74)

6.87(4.33,8.18)

6.12(5.22,7.58)

0.565

 PLT(× 10^9/L)

164.38 ± 53.48

131.77 ± 50.35

169.62 ± 52.36

0.013^*

 Glucose(mmol/L)

6.12(5.22,7.92)

6.87(4.33,8.18)

6.03(5.20,7.41)

0.176

 Albumin(g/L)

40.75(38.35,42.45)

37.76 ± 3.86

40.683.52

0.003^*

 Hs-CRP(mg/L)

1.89(0.57,4.82)

4.42(2.28,10.40)

1.72(0.47,4.38)

0.045^*

 SF(ug/L)

296.99 ± 165.25

299.37 ± 140.31

296.59 ± 169.85

0.956

eGFR(ml/min⋅1.73m²)

15.26(12.61,18.31)

15.78(14.03,20.50)

15.16(12.57,17.80)

0.788

 spKt/V

1.53 ± 0.29

1.43 ± 0.35

1.54 ± 0.28

0.168

 Phosphate(mmol/L)

1.67(1.40,2.13)

1.71(1.55,2.01)

1.66(1.40,2.14)

0.745

 Calcium(mmol/L)

2.33 ± 0.28

2.26 ± 0.23

2.35 ± 0.28

0.258

 PTH(pg/ml)

328.89(169.80,487.40)

287.43(121.31,419.14)

348.46(172.24,525.92)

0.216

Complement factors

 C3c(g/L)

0.92 ± 0.17

0.98 ± 0.21

0.91 ± 0.16

0.154

 C1q(mg/L)

201.84 ± 41.43

209.34 ± 39.79

200.44 ± 41.79

0.419

 CFH(ug/mL)

361.77 ± 57.63

388.64 ± 75.32

361.21 ± 57.06

0.169

 CFB(mg/L)

346.15(299.93,388.20)

355.5(288.55,430.70)

346.10(302.40,387.20)

0.358

 C4(g/L)

0.31(0.25,0.38)

0.33(0.28,0.49)

0.31(0.24,0.38)

0.205

 MAC (ng/mL)

482.26(307.59,783.75)

401.80(325.65,981.94)

484.32(294.83,758.05)

0.440

 C5a(ng/mL)

31.03 ± 10.80

28.13 ± 9.70

31.57 ± 10.97

0.230

 C3a(ng/mL)

238.72(190.12,318.95)

280.29(224.61,346.60)

229.03(182.10,294.49)

0.339

 MBL(ng/mL)

4346.38(1415.73,8979.95)

4096.73(923.94,8756.41)

4807.28(1466.52,9043.82)

0.471

 Primary cause of ESRD

0.415

 Primary glomerulopathy

37(34.3%)

5(29.4%)

32(35.2%)

 Diabetes

14(13.0%)

2(11.8%)

12(13.2%)

 Hypertension

14(13.0%)

4(23.5%)

10(11.0%)

 ADTKD

10(9.3%)

0

10(11.0%)

 Tubulointerstitial nephropathy

17(15.7%)

2(11.8%)

15(16.5%)

 Other or unknown

16(14.8%)

4(23.5%)

12(13.2%)

Comorbidity

 CCDs

39(36.1%)

9(52.9%)

30(33.0%)

0.116

 Hypertension

77(71.3%)

8(47.1%)

69(75.8%)

0.034^*

 Diabetes

12(11.1%)

2(11.8%)

10(11.0%)

1.000