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Table 3 Multivariable Competing-Risk Regression Analysis of Technique Failure And Cause-Specific Technique Failure Within First-Year of PD

From: Incidence and Risk Factors Associated with Technique Failure in the First Year of Peritoneal Dialysis: A Single Center Retrospective Cohort Study in Southern China

 

Technique Failure

P

Death

P

Transfer to HD

P

SHR (95% CI)

SHR (95% CI)

SHR (95% CI)

Male gender

1.06(0.70–1.63)

0.76

1.13(0.66–1.93)

0.65

1.05(0.50–2.20)

0.90

Age

   < 65Y

Reference

 

Reference

 

reference

 

   ≥ 65Y

2.78(1.82–4.30)

 < 0.001

4.36(2.46–7.74)

 < 0.001

1.22(0.53–2.34)

0.76

BMI

   < 18.5 kg/m2

1.77(1.17–2.67)

0.01

2.42(1.44–4.06)

 < 0.001

0.98(0.46–2.10)

0.96

  18.5–24 kg/m2

Reference

 

Reference

 

reference

 

   > 24 kg/m2

1.46(0.98–2.14)

0.06

1.38(0.82–2.35)

0.22

1.45(0.81–2.60)

2.06

Education

  under the primary

Reference

 

Reference

 

reference

 

  primary

1.18(0.81–1.70)

0.39

1.03(0.64–1.64)

0.91

1.43(0.76–2.66)

0.26

  higher

0.77(0.46–1.28)

0.31

0.73(0.38–1.40)

0.35

0.78(0.32–1.91)

0.60

Medical insurance

  RMI

Reference

 

Reference

 

Reference

 

  EMI

0.47(0.32–0.69)

 < 0.001

0.41(0.24–0.70)

 < 0.001

0.55(0.31–0.99)

0.05

  CI or FM

0.38(0.15–1.01)

0.05

0.41(0.14–1.24)

0.12

0.34(0.05–2.58)

0.30

Self-care ability

  not completely

Reference

 

Reference

 

reference

 

  complete

0.67(0.43–1.05)

0.08

0.53(0.32–0.88)

0.02

1.41(0.50–3.99)

0.51

Cause of ESKD

  Glomerulonephritis

Reference

 

Reference

 

reference

 

  Diabetes

0.66(0.35–1.27)

0.21

0.58(0.26–1.30)

0.17

0.96(0.32–2.89)

0.95

  Hypertension

0.80(0.38–1.67)

0.54

0.70(0.26–1.92)

0.49

1.01(0.36–2.86)

0.97

  Other

1.43(0.88–2.41)

0.17

1.30(0.64–2.65)

0.47

1.56(0.75–3.24)

0.23

Comorbidity conditions

  Diabetes

1.52(0.86–2.68)

0.15

1.93(0.95–3.92)

0.07

0.97(0.34–2.75)

0.99

  CVD

1.57(0.84–2.94)

0.16

1.72(0.85–3.49)

0.13

1.37(0.38–4.95)

0.63

  IHD

  CHF

0.67(0.36–1.24)

2.81(1.58–4.98)

0.20

 < 0.001

0.57(0.29–1.08)

3.52(1.83–6.75)

0.09

 < 0.001

1.10(0.28–4.26)

0.81(0.12–5.40)

0.88

0.83

Laboratory variables

  Hemoglobin(g/L)

1.01(0.99–1.02)

0.17

1.01(0.99–1.02)

0.15

1.00(0.98–1.02)

0.93

  Albumin(g/L)

0.93(0.89–0.96)

 < 0.001

0.92(0.88–0.96)

 < 0.001

0.95(0.90–1.00)

0.67

  Total cholesterol (mmol/L)

0.96(0.83–1.12)

0.63

1.01(0.85–1.19)

0.93

0.92(0.70–1.21)

0.53

  Triglycerides (mmol/L)

0.95(0.85–1.07)

0.42

1.10(0.88–1.36)

0.39

0.86(0.70–1.07)

0.18

  Scr(mg/dL)

0.99(0.91–1.08)

0.89

0.99(0.89–1.11)

0.88

1.00(0.89–1.14)

0.92

  eGFR(mL/min/1.73m2)

1.02(0.92–1.13)

0.76

0.98(0.85–1.12)

0.77

1.09(0.93–1.27)

0.33

Duration of RRT

  0

Reference

 

Reference

 

reference

 

   > 90

1.20(0.50–2.89)

0.68

1.36(0.45–4.05)

0.59

1.07(0.26–4.47)

0.92

   ≤ 90

1.49(1.05–2.10)

0.03

1.68(1.05–2.69)

0.03

1.29(0.75–2.23)

0.36

  Peritonitis

2.02(1.36–3.01)

 < 0.001

1.10 (0.61–1.94)

0.77

3.95(2.25–6.80)

 < 0.001

  1. N = 2,290
  2. Transplantation, death and transfer to HD was competing risk respectively
  3. Abbreviations: PD Peritoneal dialysis, RMI Resident medical insurance, EMI Employee medical insurance, CI or FM Commercial insurance or Free medical, I-PTH intact parathyroid hormone, Scr Serum creatinine, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol. GFR Glomerular filtration rate, BMI Body mass index, CVD Cardiovascular disease, ESKD End stage kidney disease, HD Hemodialysis, CHF Congestive heart failure, IHD Ischemic heart disease, PD Peritoneal dialysis, RRT Renal replacement therapy