From: First-year mortality in incident dialysis patients: results of the Peridialysis study
All | PD | HD | p-value | |
---|---|---|---|---|
N = 1,580 | N = 561 | N = 1,019 | ||
Age, years | 67.0 (54.4–74.7) | 66.3 (53.5–74.4) | 67.3 (55.2–75.0) | 0.20 |
Males | 1,012 (64.1%) | 363 (64.7%) | 649 (63.7%) | 0.69 |
BMI, kg/m2 (n = 1369) | 25.8 (22.9–29.4) | 25.8 (23.0–28.7) | 25.8 (22.8–30.0) | 0.26 |
Albumin, g/L (n = 1412) | 33.0 (28.0–37.9) | 34.9 (30.0–38.0) | 32.0 (27.0–37.0) | < 0.001 |
eGFR epi ml/min1.73 m2 | 6.7 (5.0–8.5) | 7.2 (5.7–9.3) | 6.4 (4.7–8.2) | < 0.001 |
High eGFR loss ratea n(%) | 527 (43.4%) | 134 (28.3%) | 393 (53.1%) | < 0.001 |
Renal diagnosis | ||||
Diabetic nephropathy | 386 (24.4%) | 145 (25.8%) | 241 (23.7%) | 0.33 |
Polycystic kidney disease | 105 ( 6.6%) | 45 ( 8.0%) | 60 ( 5.9%) | 0.10 |
Glomerulonephritis | 283 (17.9%) | 116 (20.7%) | 167 (16.4%) | 0.033 |
Chronic interstitial nephritis | 186 (11.8%) | 51 ( 9.1%) | 135 (13.2%) | 0.014 |
Hypertensive nephropathy | 301 (19.1%) | 117 (20.9%) | 184 (18.1%) | 0.18 |
Comorbidity | ||||
Previous myocardial infarct | 170 (10.8%) | 57 (10.2%) | 113 (11.1%) | 0.57 |
Heart failure | 262 (16.6%) | 89 (15.9%) | 173 (17.0%) | 0.57 |
Other heart disease | 196 (12.4%) | 59 (10.5%) | 137 (13.4%) | 0.091 |
Cerebrovascular | 188 (11.9%) | 60 (10.7%) | 128 (12.6%) | 0.27 |
Clinical diabetes mellitus | 548 (34.7%) | 196 (34.9%) | 352 (34.5%) | 0.87 |
Peripheral atherosclerosis | 193 (12.2%) | 57 (10.2%) | 136 (13.3%) | 0.064 |
Cancer | 261 (16.5%) | 73 (13.0%) | 188 (18.4%) | 0.005 |
Pulmonary | 150 ( 9.5%) | 44 ( 7.8%) | 106 (10.4%) | 0.097 |
Hepatic | 60 ( 3.8%) | 19 ( 3.4%) | 41 ( 4.0%) | 0.53 |
Previous transplant | 81 ( 5.1%) | 22 ( 3.9%) | 59 ( 5.8%) | 0.11 |
Psychiatric | 67 ( 4.2%) | 14 ( 2.5%) | 53 ( 5.2%) | 0.011 |
Biochemical | ||||
Hemoglobin, ref ≥ 7 mmol/L | 1,142 (73.1%) | 336 (61.0%) | 806 (79.7%) | < 0.001 |
Urea, ref = < 30 mmol/L | 876 (57.1%) | 230 (42.7%) | 646 (65.0%) | < 0.001 |
Potassium < 5 ref | 414 (26.8%) | 93 (17.0%) | 321 (32.2%) | < 0.001 |
Bicarbonate ref = < 15 mmol/L | 1,048 (89.3%) | 393 (97.5%) | 655 (85.1%) | < 0.001 |
Ionized calcium ≥ 1.15 mmol/L | 769 (51.2%) | 331 (62.0%) | 438 (45.3%) | < 0.001 |
Phosphate ≥ 2.0 mmol/L | 654 (44.2%) | 171 (32.0%) | 483 (51.2%) | < 0.001 |
Clinical complications at DI | ||||
Pulmonary stasis | 126 ( 8.2%) | 22 ( 4.0%) | 104 (10.5%) | < 0.001 |
Dyspnea | 70 ( 4.5%) | 18 ( 3.3%) | 52 ( 5.2%) | 0.075 |
Cerebral symptoms | 16 ( 1.0%) | 1 ( 0.2%) | 15 ( 1.5%) | 0.014 |
Edema | 117 ( 7.6%) | 39 ( 7.1%) | 78 ( 7.9%) | 0.58 |
Cardiac symptoms | 36 ( 2.3%) | 14 ( 2.5%) | 22 ( 2.2%) | 0.68 |
Fatigue | 293 (19.0%) | 128 (23.2%) | 165 (16.6%) | 0.001 |
Anorexia | 227 (14.7%) | 104 (18.9%) | 123 (12.4%) | < 0.001 |
Mortality rateb | ||||
0 – 3 months, n(%) | 108(23.90) | 23(14.11) | 85(29.42) | 0.001 |
3 – 6 months, n(%) | 78(18.86) | 22(14.15) | 56(21.37) | 0.12 |
6 – 9 months, n(%) | 68(17.96) | 27(19.59) | 41(17.96) | 0.56 |
9 – 12 months, n(%) | 53(15.43) | 20(16.10) | 33(15.02) | 0.80 |
0 – 12 months, n(%) | 307(19.33) | 92 (15.95) | 215(21.26) | 0.02 |