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Table 1 Clinical and laboratory characteristics in all 1580 patients initiating dialysis and when divided based upon initial therapy of PD or HD

From: First-year mortality in incident dialysis patients: results of the Peridialysis study

 

All

PD

HD

p-value

 

N = 1,580

N = 561

N = 1,019

 

Age, years

67.0 (54.4–74.7)

66.3 (53.5–74.4)

67.3 (55.2–75.0)

0.20

Males

1,012 (64.1%)

363 (64.7%)

649 (63.7%)

0.69

BMI, kg/m2 (n = 1369)

25.8 (22.9–29.4)

25.8 (23.0–28.7)

25.8 (22.8–30.0)

0.26

Albumin, g/L (n = 1412)

33.0 (28.0–37.9)

34.9 (30.0–38.0)

32.0 (27.0–37.0)

 < 0.001

eGFR epi ml/min1.73 m2

6.7 (5.0–8.5)

7.2 (5.7–9.3)

6.4 (4.7–8.2)

 < 0.001

High eGFR loss ratea n(%)

527 (43.4%)

134 (28.3%)

393 (53.1%)

 < 0.001

Renal diagnosis

 Diabetic nephropathy

386 (24.4%)

145 (25.8%)

241 (23.7%)

0.33

 Polycystic kidney disease

105 ( 6.6%)

45 ( 8.0%)

60 ( 5.9%)

0.10

 Glomerulonephritis

283 (17.9%)

116 (20.7%)

167 (16.4%)

0.033

 Chronic interstitial nephritis

186 (11.8%)

51 ( 9.1%)

135 (13.2%)

0.014

 Hypertensive nephropathy

301 (19.1%)

117 (20.9%)

184 (18.1%)

0.18

Comorbidity

 Previous myocardial infarct

170 (10.8%)

57 (10.2%)

113 (11.1%)

0.57

 Heart failure

262 (16.6%)

89 (15.9%)

173 (17.0%)

0.57

 Other heart disease

196 (12.4%)

59 (10.5%)

137 (13.4%)

0.091

 Cerebrovascular

188 (11.9%)

60 (10.7%)

128 (12.6%)

0.27

 Clinical diabetes mellitus

548 (34.7%)

196 (34.9%)

352 (34.5%)

0.87

 Peripheral atherosclerosis

193 (12.2%)

57 (10.2%)

136 (13.3%)

0.064

 Cancer

261 (16.5%)

73 (13.0%)

188 (18.4%)

0.005

 Pulmonary

150 ( 9.5%)

44 ( 7.8%)

106 (10.4%)

0.097

 Hepatic

60 ( 3.8%)

19 ( 3.4%)

41 ( 4.0%)

0.53

 Previous transplant

81 ( 5.1%)

22 ( 3.9%)

59 ( 5.8%)

0.11

 Psychiatric

67 ( 4.2%)

14 ( 2.5%)

53 ( 5.2%)

0.011

Biochemical

 Hemoglobin, ref ≥ 7 mmol/L

1,142 (73.1%)

336 (61.0%)

806 (79.7%)

 < 0.001

 Urea, ref =  < 30 mmol/L

876 (57.1%)

230 (42.7%)

646 (65.0%)

 < 0.001

 Potassium < 5 ref

414 (26.8%)

93 (17.0%)

321 (32.2%)

 < 0.001

 Bicarbonate ref =  < 15 mmol/L

1,048 (89.3%)

393 (97.5%)

655 (85.1%)

 < 0.001

 Ionized calcium ≥ 1.15 mmol/L

769 (51.2%)

331 (62.0%)

438 (45.3%)

 < 0.001

 Phosphate ≥ 2.0 mmol/L

654 (44.2%)

171 (32.0%)

483 (51.2%)

 < 0.001

Clinical complications at DI

 Pulmonary stasis

126 ( 8.2%)

22 ( 4.0%)

104 (10.5%)

 < 0.001

 Dyspnea

70 ( 4.5%)

18 ( 3.3%)

52 ( 5.2%)

0.075

 Cerebral symptoms

16 ( 1.0%)

1 ( 0.2%)

15 ( 1.5%)

0.014

 Edema

117 ( 7.6%)

39 ( 7.1%)

78 ( 7.9%)

0.58

 Cardiac symptoms

36 ( 2.3%)

14 ( 2.5%)

22 ( 2.2%)

0.68

 Fatigue

293 (19.0%)

128 (23.2%)

165 (16.6%)

0.001

 Anorexia

227 (14.7%)

104 (18.9%)

123 (12.4%)

 < 0.001

Mortality rateb

 0 – 3 months, n(%)

108(23.90)

23(14.11)

85(29.42)

0.001

 3 – 6 months, n(%)

78(18.86)

22(14.15)

56(21.37)

0.12

 6 – 9 months, n(%)

68(17.96)

27(19.59)

41(17.96)

0.56

 9 – 12 months, n(%)

53(15.43)

20(16.10)

33(15.02)

0.80

 0 – 12 months, n(%)

307(19.33)

92 (15.95)

215(21.26)

0.02

  1. Data are presented as n (%) for categorial measures and median (IQR, interquartile range) for continuous variables
  2. aeGFR loss > 1 ml/min1.73m2/month during 3 to 0 months prior to DI /month
  3. bn (%), Number of deaths (deaths per 100 patient-years for each interval)