Table 1 Baseline Characteristics of the study populations and subpopulations
Characteristic | Training dataset (n = 643) | Validation dataset (n = 173) | P-value |
|---|---|---|---|
Age at diagnosis (years), mean ± SD | 57.41 ± 15.84 | 57.50 ± 16.21 | 0.421 |
Male | 311(48.37) | 84(48.55) | 0.399 |
Body mass index (kg/m2) | 21.49 ± 3.20 | 21.32 ± 3.13 | 0.187 |
Smokers n (%) | 76(11.82) | 22(12.72) | 0.451 |
Diabetes n (%) | 202 (31.42) | 66 (32.20) | 0.289 |
Hypertension n (%) | 589(91.60) | 153(88.44) | 0.081 |
Intradialytic hypotension | 195(30.32) | 48(27.75) | 0.261 |
Cardiovascular disease n (%) | 231(35.93) | 65(37.57) | 0.687 |
Systolic blood pressure (mmHg) | 142.22 ± 21.31 | 141.53 ± 22.05 | 0.573 |
Diastolic blood pressure (mmHg) | 85.24 ± 32.22 | 83.35 ± 15.71 | 0.311 |
Serum creatinine (umol/L) | 802.32 ± 353.13 | 799.32 ± 345.89 | 0.282 |
Serum uric acid (umol/L) | 418.00(179.75) | 413.50(181.25) | 0.832 |
Blood urea nitrogen(BUN) | 22.45(14.17) | 23.54(13.11) | 0.613 |
Hemoglobin (g/L) | 89.39 ± 22.51 | 88.82 ± 22.12 | 0.413 |
White blood cell count(109 /L) | 6.34 ± 3.12 | 6.29 ± 3.51 | 0.424 |
Serum albumin (g/L) | 33.85 ± 6.80 | 32.99 ± 6.59 | 0.829 |
Serum calcium (mmol/L) | 2.09 ± 0.51 | 2.07 ± 0.21 | 0.622 |
Serum phosphorus (mmol/L) | 1.89 ± 0.53 | 1.82 ± 0.62 | 0.981 |
Serum potassium(mmol/L) | 4.38 ± 0.83 | 4.56 ± 0.80 | 0.431 |
Triglycerides (mmol/L) | 1.32(0.92) | 1.35(0.90) | 0.892 |
Total cholesterol (mmol/L) | 4.18(1.49) | 4.22(1.41) | 0.792 |
Low density lipoprotein (mmol/L) | 2.28(1.24) | 2.35(1.13) | 0.594 |
Hs-CRP (g/mL) | 6.50(12.00) | 6.60(12.60) | 0.813 |
PTH (pg/ml) | 246.35(285.40) | 339.12(398.76) | 0.252 |
24 h urine output < 400 ml | 263(40.90) | 66(38.15) | 0.175 |
Kt/V | 1.23 ± 0.32 | 1.26 ± 0.26 | 0.441 |
eGFR (ml/min/1.73m2) | 5.38(4.05) | 5.52(4.21) | 0.438 |
ACEi or ARB n (%) | 212(32.97) | 56(32.37) | 0.539 |
CCB n (%) | 432(67.19) | 126(72.83) | 0.171 |
The initial dialysis access | |||
(1)Use of AVF n (%) | 196(30.48) | 50(28.90) | 0.190 |
(2)Use of semi-permanent dialysis catheter n (%) | 88(13.69) | 34(19.65) | 0.120 |
(3)temporary dialysis catheter n (%) | 359(55.83) | 89(51.45) | 0.253 |