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Fig. 5 | BMC Nephrology

Fig. 5

From: 1,25-dihydroxyvitamin D3 ameliorates lupus nephritis through inhibiting the NF-κB and MAPK signalling pathways in MRL/lpr mice

Fig. 5

1,25-dihydroxyvitamin D3 reduced lupus activity and inhibited the pro-inflammatory cytokines. A The concentrations of A-ds DNA and C3 in the serum. B-D The concentrations of TNF-α, IL-17, and MCP-1 in the serum and kidneys. Values are expressed as means ± SD (n = 6/group). * VS. the control group at the same time. # VS. the control group at 14 weeks. VS. the treated group at 14 weeks. *# p < 0.05, **##p < 0.01, ***###p < 0.001

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