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Table 2 Clinical features and outcomes of PLA2R positive HBV-MN patients and idiopathic MN patients

From: Favorable outcome in PLA2R positive HBV-associated membranous nephropathy

 

HBV-MN (7)

Idiopathic MN (71)

P value

Baseline clinical characteristics

 Gender(male/female)

2/5

48/23

0.091

 Age

45 (31, 59)

53 (42, 61)

0.426

 eGFR (ml/min/1.73m2)

107.8 (102.1, 125.9)

98.3 (86.0, 109.6)

0.170

 Urinary Pro (g/24h)

4.97 (2.48, 9.48)

4.74 (2.38, 8.09)

0.727

 Urine RBC (/μL)

94.5 (71.7, 204.8)

64.9 (17.1, 105.3)

0.085

 ALB (g/L)

24.43±5.15

26.33±6.15

0.432

 Hypocomplementemia, n (%)

3/6 (50.0)

12/60 (20.0)

0.125

Remission without IS

 

0.048

 NIS-Remission, n (%)

6 (85.7)

31 (43.7)

 

 NIS-NR, n (%)

0 (0)

6 (8.5)

 

 IS, n (%)

1 (14.3)

34 (47.9)

 

Renal insufficiency, n (%)

0 (0)

8 (11.3)

1.000

  1. PLA2R Phospholipase A2 receptor, MN Membranous nephropathy, eGFR estimated glomerular filtration rate, Pro Protein, RBC Red blood cell, ALB Serum Albumin, HBsAg Hepatitis B virus surface antigen, HBeAg Hepatitis B virus e antigen, NIS Non-immunosuppressive therapy, NR No remission, IS Immunosuppressive therapy