Favorable outcome in PLA2R positive HBV-associated membranous nephropathy

BMC Nephrology

Table 3 Pathological features of the 7 patients with PLA2R positive HBV associated MN

Patient	Light microscope			Immunofluorescence								Electronic microscope
Patient	Sclerotic glomeruli	Segmental sclerosis	Mesangial proliferation	IgG	IgA	IgM	C3	C1q	C4	HBsAg/HBcAg	PLA2R-Ag	Subepithelial EDs	Mesangial EDs
1	0/22	0/22	±	1+	±	+	±	-	-	+/-	+	+	+
2	1/40	0/40	±	3+	-	-	2+	-	-	+/-	+	+	+
3	0/23	0/23	±	3+	-	+	1+	-	ND	+/-	+	+	±
4	0/5	0/5	±	2+	-	-	1+	-	-	+/-	+	+	-
5	0/19	1/19	+	4+	+	-	3+	-	-	+/+	+	+	+
6	1/2	0/2	₊	2+	-	-	-	-	-	-/+	+	+	-
7	1/17	0/17	±	3+	-	+	2+	-	-	+/+	+	+	+

HBsAg Hepatitis B virus surface antigen, HBcAg Hepatitis B virus core antigen, PLA2R-Ag Phospholipase 2 receptor antigen, ED Electron dense deposit, ND No data

ISSN: 1471-2369