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Table 2 Changes in study outcomes

From: A 6-Month clinical practice pilot study of sucroferric oxyhydroxide on nutritional status in patients on peritoneal dialysis

  

Time-point

  

Variable

Baseline (BL)

3 Month (M3)

6 Month (M6)

P-Value

All participants (n)

n = 17

n = 12

n = 11b

 

 Phosphorus, mg/dLa

7.47 ± 1.76

5.63 ± 0.88

5.69 ± 1.72

 < 0.001

 Albumin, g/dL

3.49 ± 0.37

3.61 ± 0.27

3.50 ± 0.27

0.25

 Phosphorus-attuned albumin, x103a

0.49 ± 0.12

0.65 ± 0.10

0.67 ± 0.21

 < 0.05

 Calcium, mg/dLa

8.22 ± 1.03

8.83 ± 0.84

8.63 ± 1.13

 < 0.001

 Intact PTH, pg/mL

416 (292–631)

382 (128–578)

361 (237–540)

0.33

Completed participants (n = 12)

 Phosphorus, mg/dLa

7.17 ± 1.76

5.69 ± 0.89

5.69 ± 1.72

 < 0.001

 Albumin, g/dL

3.42 ± 0.38

3.56 ± 0.24

3.5 ± 0.27

0.21

 Phosphorus-attuned albumin, x103a

0.50 ± 0.13

0.64 ± 0.09

0.67 ± 0.21

0.02

 Calcium, mg/dLa

8.13 ± 1.17

8.75 ± 0.83

8.63 ± 1.13

 < 0.01

 Intact PTH, pg/mL

340 (166–462)

377 (128–578)

361 (237–540)

0.37

Dietary Intake

 Calories

1621 ± 648

1383 ± 868

1575 ± 567

0.42

 Calories/kg

20.9 ± 11.1

18.1 ± 13.6

20.2 ± 9.0

0.53

 Protein, g

77 ± 35

62 ± 38

74 ± 39

0.16

 Protein, g/kg

1.0 ± 0.6

0.8 ± 0.6

1.0 ± 0.6

0.21

 Phosphorus, mg

1159 ± 525

973 ± 685

1097 ± 419

0.36

  1. All values are presented as mean ± standard deviation, except PTH is reported as median (interquartile range). PTH, parathyroid hormone. a BL different from 3 and 6 M (P value < 0.05). b One subject not accounted for (n = 12) was an early end of study visit