The pathological and outcome characteristics of renal lesions in Crohn’s disease

BMC Nephrology

Table 4 Primary kidney biopsy findings and renal outcome from the diagnosis of renal disease to six-month and twelve-month treatment by urinalysis^a in 20 patients with Crohn’s disease

		Six-month follow-up		Twelve-month follow-up
Diagnosis	Patients (n/N)	Outcome of proteinuria	Outcome of hematuria	Outcome of proteinuria	Outcome of hematuria
IgA nephropathy	14/20	10 (CR^b), 2 (PR^c), and two missing data	3 (CR^b), 4 (PR^c), 5 (R^d), and two missing data	9 (CR^b), 2 (R^d), and three missing data	5 (CR^b), 4 (PR^c), 2 (R^d), and three missing data
Minimal change disease	2/20	2 (CR^b)	1 (CR^b) and 1 (R^d)	2 (CR^b)	1 (CR^b) and 1 (PR^c)
Acute interstitial nephritis	1/20	1 (CR^b)	1 (CR^b)	1 (CR^b)	1 (CR^b)
Granulomatous interstitial nephritis	1/20	1 (CR^b)	1 (CR^b)	1 (CR^b)	1 (CR^b)
non-IgA mesangial proliferative nephritis	1/20	1 (CR^b)	1 (R^d)	1 (CR^b)	1 (R^d)
Thin-basement-membrane nephropathy	1/20	1 (CR^b)	1 (R^d)	1 (CR^b)	1 (PR^c)

^a Two and three patients were excluded due to a lack of follow-up data at six months and twelve months respectively
^b Complete remission (CR) was defined as urinalysis change from negative, trace or ≥ 1 + to negative or trace
^c Partial remission (PR) was considered to be present if urinalysis decreased more than one stage but remained ≥ 1 +
^d Relapse (R) was defined as urinalysis change from negative or trace to ≥ 1 + or increased more than one stage but remained ≥ 1 +

ISSN: 1471-2369