VARIABLES | Low-grade albuminuria terciles (unit) | p-value | ||
---|---|---|---|---|
Tercile 1 (≤ 3.0) | Tercile 2 (4.0–7.0) | Tercile 3 (≥ 8.0) | ||
n (%) | ||||
Smokers | 14 (42.4) | 10 (30.3) | 9 (27.3) | 0.899* |
Alcohol users | 41 (38.0) | 31 (28.7) | 36 (33.3) | 0.226* |
Obesity | 14 (37.8) | 12 (32.4) | 11 (29.7) | 0.979* |
HBPa | 78 (37.9) | 66 (33.0) | 60 (29.1) | 0.616* |
Diabetes | 37 (33.9) | 38 (34.9) | 34 (31.2) | 0.340* |
Cardiovascular risk > 20%b | 54 (35.1) | 51 (33.1) | 49 (31.8) | 0.156* |
Metabolic syndrome | 45 (40.2) | 36 (32.1) | 31 (27.7) | 0.882* |
Statins | 18 (31.0) | 19 (32.8) | 21 (36.2) | 0.235* |
Lipid lowering medications | 0 (0.0) | 1 (33.3) | 2 (66.7) | 0.253* |
Diuretics | 38 (37.3) | 42 (41.2) | 22 (21.6) | 0.028* |
Adrenergic Blockers | 10 (27.8) | 17 (47.2) | 9 (25.0) | 0.119* |
Direct-Acting Vasodilators | 1 (25.0) | 1 (25.0) | 2 (50.0) | 0.623* |
Calcium Channel Blockers (CCBs) | 8 (27.6) | 13 (44.8) | 8 (27.6) | 0.276* |
Angiotensin-Converting Enzyme Inhibitors (ACEIs) | 27 (37.0) | 24 (32.9) | 22 (30.1) | 0.899* |
Angiotensin II AT1 Receptor Blockers (ARBs) | 24 (32.4) | 30 (40.5) | 20 (27.0) | 0.196* |
Insulin | 11 (39.3) | 9 (32.1) | 8 (28.6) | 0.997* |
Metformin | 23 (34.3) | 24 (35.8) | 20 (29.9) | 0.655* |
Sulfonylureas | 7 (35.0) | 6 (30.0) | 7 (35.0) | 0.789* |
SGLT2 inhibitor | 0 (0.0) | 1 (100.0) | 0 (0,0) | 0.357* |
DPP-4 inhibitor | 0 (0.0) | 0 (0.0) | 1 (100.0) | 0.282* |
μ (Standard deviation) | ||||
Age (years) | 59.1 ± 11.7 | 61.2 ± 12.1 | 62.8 ± 13.0 | 0.170** |
BMIc (kg/m2) | 27.3 ± 4.5 | 27.6 ± 4.8 | 26.9 ± 4.3 | 0.638** |
SBPd(mm/Hg) | 132.2 ± 17.3 | 132.0 ± 18.1 | 135.2 ± 17.8 | 0.485** |
DBPe (mm/Hg) | 81.3 ± 10.5 | 83.1 ± 10.2 | 83.8 ± 9.3 | 0.257** |
Total cholesterol (mg/dL) | 187.0 ± 37.5 | 187.7 ± 38.4 | 193.7 ± 42.6 | 0.532** |
HDLf (mg/dL) | 48.0 ± 12.6 | 49.0 ± 12.1 | 47.4 ± 13.8 | 0.755** |
GFRg(mL/min/1.73m2) | 83.0 ± 16.5 | 87.0 ± 20.0 | 81.5 ± 24.0 | 0.238** |
Framinghan score (points) | 26.7 ± 17.1 | 28.6 ± 15.7 | 33.6 ± 17.8 | 0.042** |
median (IR 25–75) | ||||
Glycated hemoglobin (%) | 5.7 (5.5–6.2) | 6.0 (5.7–6.9) | 6.0 (5.6–6.9) | 0.005*** |
Glucose (mg/dL) | 94.0 (86.0–114.0) | 96.0 (90.0–141.0) | 105.0 (90.0–135.0) | 0.021*** |
Triglycerides (mg/dL) | 113.0 (89.0–152.0) | 112.0 (84.0–165.0) | 137.0 (89.0–198.0) | 0.213*** |