VARIABLES | Low-grade albuminuria terciles (unit) | p-value | ||
---|---|---|---|---|
Tercile 1 (≤ 3.0) | Tercile 2 (4.0–7.0) | Tercile 3 (≥ 8.0) | ||
n (%) | ||||
Smokers | 11 (28.9) | 14 (36.8) | 13 (34.2) | 0.679* |
Alcohol users | 23 (34.8) | 27 (40.9) | 16 (24.2) | 0.692* |
Obesity | 46 (31.3) | 61 (41.5) | 40 (27.2) | 0.543* |
HBPa | 129 (33.8) | 145 (38.0) | 108 (28.3) | 0.942* |
Diabetes | 54 (29.5) | 67 (36.6) | 62 (33.9) | 0.072* |
Cardiovascular risk > 20%b | 33 (28.7) | 44 (38.3) | 38 (33.0) | 0.311* |
Metabolic syndrome | 96 (32.9) | 108 (37.0) | 88 (30.1) | 0.568* |
Statins | 50 (36.2) | 48 (34.8) | 40 (29.0) | 0.599 |
Lipid lowering medications | 1 (20.0) | 2 (50.0) | 1 (25.0) | 0.879 |
Diuretics | 80 (36.5) | 78 (35.6) | 61 (27.9) | 0.371 |
Adrenergic Blockers | 39 (33.3) | 41 (35.00) | 37 (31.6) | 0.617 |
Direct-Acting Vasodilators | 3 (33.3) | 2 (22.2) | 4 (44.4) | 0.489 |
Calcium Channel Blockers (CCBs) | 26 (35.6) | 28 (38.4) | 19 (26.0) | 0.863 |
Angiotensin-Converting Enzyme Inhibitors (ACEIs) | 33 (32.7) | 34 (33.7) | 34 (33.7) | 0.370 |
Angiotensin II AT1 Receptor Blockers (ARBs) | 55 (34.4) | 66 (41.2) | 39 (24.4) | 0.315 |
Insulin | 11 (37.9) | 8 (27.6) | 10 (34.5) | 0.480 |
Metformin | 35 (29.4) | 46 (38.7) | 38 (31.9) | 0.447 |
Sulfonylureas | 11 (24.4) | 14 (31.1) | 20 (44.4) | 0.040 |
SGLT2 inhibitor | 0 (0.0) | 1 (100.0) | 0 (0.0) | 0.441 |
DPP-4 inhibitor | 2 (100.0) | 0 (0.0) | 0 (0.0) | 0.137 |
μ (Standard deviation) | ||||
Age (years) | 59.1 ± 11.6 | 61.3 ± 11.0 | 64.2 ± 11.6 | 0.002** |
BMIc (kg/m2) | 30.2 ± 5.7 | 30.6 ± 6.6 | 29.1 ± 5.3 | 0.139** |
SBPd(mm/Hg) | 130.1 ± 16.6 | 131.7 ± 16.8 | 135.3 ± 22.0 | 0.074** |
DBPe (mm/Hg) | 80.9 ± 10.8 | 80.2 ± 10.5 | 81.3 ± 10.9 | 0.674** |
Total cholesterol (mg/dL) | 196.5 ± 38.7 | 195.7 ± 38.6 | 184.3 ± 40.7 | 0.025** |
HDLf (mg/dL) | 54.3 ± 13.0 | 51.8 ± 12.2 | 52.6 ± 13.7 | 0.236** |
GFRg(mL/min/1.73m2) | 82.7 ± 17.4 | 87.0 ± 18.1 | 84.5 ± 19.9 | 0.141** |
Framinghan score (points) | 14.2 ± 10.8 | 16.2 ± 11.6 | 18.1 ± 12.6 | 0.029** |
median (min – max) | ||||
Glycated hemoglobin (%) | 5.9 (5.6–6.0) | 5.9 (5.5–6.8) | 6.2 (5.8–7.3) | 0.006*** |
Glucose (mg/dL) | 95.0 (87.0–118.0) | 96.0 (87.0–120.0) | 101.5 (87.5–141.0) | 0.216*** |
Triglycerides (mg/dL) | 120.0 (93.0–163.0) | 136.0 (104.0–177.0) | 126.5 (102.5–165.0) | 0.051*** |