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Table 3 The demographic and clinical characteristics according to the terciles of low-grade albuminuria, adjusted for the female population, Viçosa – MG

From: Low-grade albuminuria and its relationship with cardiovascular disease risk in hypertensive and diabetic patients in primary health care

VARIABLES

Low-grade albuminuria terciles (unit)

p-value

Tercile 1 (≤ 3.0)

Tercile 2 (4.0–7.0)

Tercile 3 (≥  8.0)

 

n (%)

 

Smokers

11 (28.9)

14 (36.8)

13 (34.2)

0.679*

Alcohol users

23 (34.8)

27 (40.9)

16 (24.2)

0.692*

Obesity

46 (31.3)

61 (41.5)

40 (27.2)

0.543*

HBPa

129 (33.8)

145 (38.0)

108 (28.3)

0.942*

Diabetes

54 (29.5)

67 (36.6)

62 (33.9)

0.072*

Cardiovascular risk > 20%b

33 (28.7)

44 (38.3)

38 (33.0)

0.311*

Metabolic syndrome

96 (32.9)

108 (37.0)

88 (30.1)

0.568*

Statins

50 (36.2)

48 (34.8)

40 (29.0)

0.599

Lipid lowering medications

1 (20.0)

2 (50.0)

1 (25.0)

0.879

Diuretics

80 (36.5)

78 (35.6)

61 (27.9)

0.371

Adrenergic Blockers

39 (33.3)

41 (35.00)

37 (31.6)

0.617

Direct-Acting Vasodilators

3 (33.3)

2 (22.2)

4 (44.4)

0.489

Calcium Channel Blockers (CCBs)

26 (35.6)

28 (38.4)

19 (26.0)

0.863

Angiotensin-Converting Enzyme Inhibitors (ACEIs)

33 (32.7)

34 (33.7)

34 (33.7)

0.370

Angiotensin II AT1 Receptor Blockers (ARBs)

55 (34.4)

66 (41.2)

39 (24.4)

0.315

Insulin

11 (37.9)

8 (27.6)

10 (34.5)

0.480

Metformin

35 (29.4)

46 (38.7)

38 (31.9)

0.447

Sulfonylureas

11 (24.4)

14 (31.1)

20 (44.4)

0.040

SGLT2 inhibitor

0 (0.0)

1 (100.0)

0 (0.0)

0.441

DPP-4 inhibitor

2 (100.0)

0 (0.0)

0 (0.0)

0.137

 

μ (Standard deviation)

 

Age (years)

59.1 ± 11.6

61.3 ± 11.0

64.2 ± 11.6

0.002**

BMIc (kg/m2)

30.2 ± 5.7

30.6 ± 6.6

29.1 ± 5.3

0.139**

SBPd(mm/Hg)

130.1 ± 16.6

131.7 ± 16.8

135.3 ± 22.0

0.074**

DBPe (mm/Hg)

80.9 ± 10.8

80.2 ± 10.5

81.3 ± 10.9

0.674**

Total cholesterol (mg/dL)

196.5 ± 38.7

195.7 ± 38.6

184.3 ± 40.7

0.025**

HDLf (mg/dL)

54.3 ± 13.0

51.8 ± 12.2

52.6 ± 13.7

0.236**

GFRg(mL/min/1.73m2)

82.7 ± 17.4

87.0 ± 18.1

84.5 ± 19.9

0.141**

Framinghan score (points)

14.2 ± 10.8

16.2 ± 11.6

18.1 ± 12.6

0.029**

 

median (min – max)

 

Glycated hemoglobin (%)

5.9 (5.6–6.0)

5.9 (5.5–6.8)

6.2 (5.8–7.3)

0.006***

Glucose (mg/dL)

95.0 (87.0–118.0)

96.0 (87.0–120.0)

101.5 (87.5–141.0)

0.216***

Triglycerides (mg/dL)

120.0 (93.0–163.0)

136.0 (104.0–177.0)

126.5 (102.5–165.0)

0.051***

  1. * Chi-squared test; ** ANOVA; *** Wilcoxon test; IR: interquartile range
  2. a high blood pressure; b 10-year risk of cardiovascular event greater than 20%; c body mass index; d systolic blood pressure; e diastolic blood pressure; f High-density lipoprotein (HDL) cholesterol; glomerular filtration rate