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Table 1 Comparison of clinical characteristics between the two groups

From: Diagnostic value of triglyceride and cystatin C ratio in diabetic kidney disease: a retrospective and prospective cohort study based on renal biopsy

Clinical parameters

DKD Group(n = 25)

NDKD Group(n = 34)

Z/t/x2

P value

Male(number, %)

17(68)

18(53)

1.354

0.245

Age (years,‾x ± s)

48.36 ± 12.26

53.12 ± 10.90

-1.571

0.122

Hypertension(number, %)

19(76)

20(59)

1.897

0.168

Tobacco smoking(number, %)

8(32)

4(12)

3.641

0.056

Alcohol drinking(number, %)

2(8)

5(15)

0.620

0.431

DR(number, %)

14(56)

4(12)

13.297

 < 0.001

BMI [kg/m2, M (Q1, Q3)]

24.97(22.54,26.26)

22.86(21.48,27.68)

-0.784

0.433

SBP(mmHg, ‾x ± s)

154.48 ± 22.95

138.56 ± 17.04

3.060

0.003

DBP [mmHg, M(Q1,Q3)]

87(80,100)

80(73,94)

-1.169

0.242

Diabetes duration [month, M (Q1, Q3)]

60(24,132)

12(6,72)

-2.418

0.016

HbA1C [%, M (Q1, Q3)]

7.00(5.75,9.37)

7.10(6.70,7.90)

-0.133

0.894

Hb (g/L, ‾x ± s)

113.40 ± 21.32

135.15 ± 20.34

-3.977

 < 0.001

FPG (mmol/L, ‾x ± s)

8.12 ± 3.43

6.80 ± 2.08

1.716

0.095

ALB(g/L,‾x ± s)

34.09 ± 7.63

30.94 ± 9.39

1.379

0.173

TC (mmol/L,‾x ± s)

6.08 ± 1.94

8.00 ± 2.96

-3.020

0.004

TG [mmol/L, M (Q1, Q3)]

1.57(1.22,1.98)

2.95(1.62,4.24)

-2.715

0.007

HDL-C (mmol/L,‾x ± s)

1.34 ± 0.38

1.47 ± 0.46

-1.140

0.259

LDL-C [mmol/L, M (Q1, Q3)]

2.97(2.42,4.40)

3.90(3.04,6.35)

-1.902

0.057

Cys-C [mg/L, M(Q1,Q3)]

1.11(0.89,1.74)

0.83(0.69,0.92)

-3.944

 < 0.001

TG/Cys-C ratio [M(Q1,Q3)]

1.24(0.75,1.91)

2.78(1.82,5.01)

-4.126

 < 0.001

Scr [umol/L, M(Q1,Q3)]

118.00(73.75,145.50)

64.00(47.00,82.00)

-3.399

0.001

UA (umol/L, ‾x ± s)

319.57 ± 75.78

346.39 ± 84.90

-1.254

0.215

eGFR(ml/min /1.73m2, x ± s)

72.30 ± 36.59

104.20 ± 40.54

-3.110

0.003

UPE, [g/24 h, M(Q1,Q3)]

5.04(3.89,8.00)

3.83(2.14,7.47)

-0.895

0.371

Hematuria(number, %)

16(64)

19(56)

0.600

0.438

FIB (g/L,‾x ± s)

4.34 ± 1.52

4.27 ± 1.13

0.199

0.843

  1. DR diabetic retinopathy, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HbA1c hemoglobin A1c, Hb hemoglobin, FPG fasting blood-glucose, ALB albumin, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein Cholesterol, LDL-C low-density lipoprotein cholesterol, Cys-C Cystatin C, TG/Cys-C ratio Triglyceride / cystatin C ratio, Scr Serum creatinine, UA uric acid, eGFR estimated glomerular filtration rate, UPE urinary protein excretion obtained over 24 h, FIB Fibrinogen