Table 4 The effects of synbiotics and placebo supplementation on constipation-related quality of life based on PAC-QOL questionnaire

Physical discomfort (questions 1-4), median (IQR)

2 (0-8)

0 (0-2)

2 (0-11)

0.5 (0-10)

0.007^a

Psychosocial discomfort

(questions 5-12), median (IQR)

2 (0-16)

0 (0-3)

3 (0-12)

2 (0-11)

0.000^a

Worries/concerns

(questions 13-23), median (IQR)

6 (2-29)

0 (0-9)

4.5 (0-24)

3 (0-12)

0.001^a

Satisfaction

(questions 24-28), median (IQR)

8 (4-12)

9 (7-13)

9.5 (2-17)

8.5 (4-14)

0.609^a

Total score, median (IQR)

18 (10-57)

11 (8-21)

18 (10-44)

16 (7-33)

0.001^a