Haemostatic profile of children with nephrotic syndrome attending University of Nigeria Teaching Hospital Ituku-Ozalla, Nigeria

Table 2 Coagulation profile of children with and without nephrotic syndrome

Variable (unit) (Ref range)	Children with nephrotic syndrome	Children without nephrotic syndrome	p value
Fibrinogen (g/L) (1.5–3.5)
Median	2.9	2.9	*0.568*
IQR	2.1 -4.9	2.3 – 3.4
95% CI of Mean	2.9 – 3.9	2.7 – 3.2
APTT (s) (36–50)
Median	45.0	42.0	0.021*
IQR	39.0 -57.0	38.0—45.3
95% CI of Mean	45.48 – 53.12	40.7 – 45.9
PT (s) (11–16)
Median	12.0	13.0	0.004*
IQR	11.0 – 13.0	12.0 – 14.0
95% CI of Mean	11.2 – 14.3	12.7 – 14.2
INR (0.8–1.2)
Median	0.9	1.0	0.009*
IQR	0.8 – 1.0	1.0 -1.1
95% CI of Mean	0.9 – 1.1	1.0 – 1.1
Platelet Count (x10³cells/mm³) (150–400)
Median	258	235	*0.310*
IQR	181 – 339	197 – 278
95% CI of Mean	240 – 308	225 – 267

SD Standard deviation, IQR Inter-quartile range, APTT Activated partial thromboplastin time, PT Prothrombin time, INR International normalized ratio, AT Antithrombin, CI Confidence interval
^* Statistically significant (p < 0.05)

ISSN: 1471-2369