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Table 3 Coagulation profile in various disease state and control

From: Haemostatic profile of children with nephrotic syndrome attending University of Nigeria Teaching Hospital Ituku-Ozalla, Nigeria

 

New Disease

Relapse

Remission

Control

Group p value

ND vs Rel

ND vs Rem

ND vs Con

Rel. Vs Rem

Rel. Vs Con

Rem vs Con

Sample size (N)

7

19

20

46

       

Fibrinogen (g/l) (1.5 – 3.5)

 Median

           

 Median

4.9

4.1

2.3

3.0

0.001*

 > 0.05

 > 0.05

 > 0.05

0.001*

 > 0.05

0.001*

 IQR

0.9 -6.2

2.3 – 5.5

1.9 – 2.6

2.4 – 4.0

       

AT (%) (80–140)

 Median

141.0

142.0

143.5

131.0

0.334

 > 0.05

 > 0.05

 > 0.05

 > 0.05

 > 0.05

 > 0.05

 IQR

118.0 – 148.0

128.0 – 152.0

130.5 -149.0

125.0 -146.0

       

APTT (s) (36 -50)

 Median

43.0

46.0

39.8 -50.0

42.0

0.148

 > 0.05

 > 0.05

 > 0.05

 > 0.05

 > 0.05

 > 0.05

 IQR

38.0 – 69.5

39.8 -68.3

 

38.0 -45.3

       
  1. ND New Disease, Con Control, Rel Relapse, Rem Remission, SD Standard deviation, IQR Inter-quartile range, Plt Platelet, APTT Activated partial thromboplastin time, PT Prothrombin time, INR International normalized ratio, AT Antithrombin, Fib Fibrinogen
  2. * Statistically significant (p < 0.05)