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Table 2 Comparison of pathological features between the two groups of patientsa

From: The clinical and pathological characteristics of IgA nephropathy patients in Tibet

 

Tibetan group (n = 70)

Beijing group (n = 977)

P Value

M0/M1

19/51

345/632

0.166

E0/E1

36/34

597/380

0.11

S0/S1

26/44

291/686

0.196

T0/T1/T2

43/20/7

489/356/132

0.183

C0/C1/C2b

24/34/9

257/466/70

0.312

IgA deposits

2.5 [2.0, 3.0]

3.0 [3.0, 3.5]

 < 0.001

IgG deposits

0.0 [0.0, 0.0]

0.0 [0.0, 0.0]

0.087

IgM deposits

1.0 [0.0, 1.1]

0.5 [0.0, 1.0]

0.613

C3 deposits

1.0 [0.5, 2.0]

2.5 [2.0, 3.0]

 < 0.001

C1q deposits

0.0 [0.0, 0.0]

0.0 [0.0, 0.0]

0.779

  1. M Mesangial hypercellularity, M0 < 50% of glomeruli showing mesangial hypercellularity, M1 > 50% of glomeruli showing mesangial hypercellularity, E Endocapillary hypercellularity, E0 No endocapillary hypercellularity, E1 Any glomeruli showing endocapillary hypercellularity, S Segmental glomerulosclerosis, S0 absent, S1 Present in any glomeruli, T Tubular atrophy/interstitial fibrosis, T0 0–25% of cortical area, T1 26–50% of cortical area, T2 > 50% of cortical area, C Cellular or fibro-cellular crescents, C0 absent, C1 0–25% of glomeruli, C2 ≥ 25% of glomeruli
  2. aSome renal biopsy samples could not be scored by the MEST-C scoring system due to few glomeruli
  3. bThere were no C classification in the early cases. Sixty-seven patients in the Tibetan group and 793 patients in the Beijing group had C scores