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Table 4 Results of the univariate logistic regression analysis

From: Prediction model of delayed graft function based on clinical characteristics combined with serum IL-2 levels

Variables

Univariate analysis

OR

95%CI

P

Recipient characteristics

 Age, yr

1.015

(0.971–1.061)

0.511

 Gender

0.938

(0.329–2.671)

0.904

BMI, kg/m2

1.065

(0.942–1.203)

0.313

Time on dialysis, m

1.008

(0.995–1.021)

0.239

Dialysis,HD

1.295

(0.534–3.143)

0.568

Immunosuppression regimen

1.056

(0.314–3.544)

0.930

Pre-Tx Creatinine, mg/dL

1.000

(0.988–1.002)

0.987

history of hypertension

0.258

(0.065–1.027)

0.055

history of diabetes mellitus

NA

NA

NA

Donor characteristics

 Age, yr

1.004

(0.976–1.032)

0.787

 Gender

3.500

(0.713–17.176)

0.123

BMI, kg/m2

1.022

(0.890–1.173)

0.760

Terminal Creatinine, mg/dL

2.279

(1.395–3.722)

0.001

The donor type

  

0.499

 DCD

REF

 DBD

1.714

(0.228–12.890)

0.601

 DBCD

0.811

(0.134–4.907)

0.819

Donor history of hypertension

3.419

(1.206–9.695)

0.021

Donor history of diabetes mellitus

5.385

(1.641–17.664)

0.005

Transplant characteristics

 CIT,h

1.438

(1.143–1.809)

0.002

 HLA mismatches

1.000

(0.692–1.444)

0.998

Donor serum markers

 IL-2(pg/mL)

1.036

(1.013–1.059)

0.002

 IL-4(pg/mL)

0.857

(0.663–1.107)

0.238

 IL-6(pg/mL)

0.800

(0.595–1.076)

0.140

 IL-10(pg/mL)

1.007

(0.990–1.025)

0.407

 CTLA-4(pg/mL)

1.000

(0.992–1.008)

0.908

 IL-35(pg/mL)

1.002

(0.834–1.205)

0.982

HMGB1(pg/mL)

1.000

(1.000–1.000)

0.481

Recipient serum markers

 IL-2(pg/mL)

0.990

(0.968–1.013)

0.990

 IL-4(pg/mL)

1.128

(0.826–1.539)

0.449

 IL-6(pg/mL)

0.881

(0.623–1.247)

0.476

 IL-10(pg/mL)

0.993

(0.969–1.017)

0.553

 CTLA-4(pg/mL)

1.000

(0.990–1.009)

0.960

 IL-35(pg/mL)

1.008

(0.815–1.245)

0.943

Treg frequency(%)

1.042

(0.848–1.281)

0.695

  1. ATG Anti-thymocyte globulin, Tac Tacrolimus, MMF Mycophenolate Mofetil, Pre-Tx Pre-transplant, HD Hemodialysis, CIT Cold ischemia time, HLA Human leukocyte antigen, DCD, Donation after cardiac death, DBD Donation after brain death, DBCD Donation after brain death plus cardiac death, BMI Body mass index, CTA cytotoxic T-lymphocyte-associated protein, CD Cluster of differentiation, IL Interleukin; HMGB1 high mobility group box 1 protein, Treg Regulatory T cells; NA Not available