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Table 4 Cox regression analysis: primary combined, and secondary renal and cardiovascular endpoints influencing factors

From: Left ventricular myocardial mass index associated with cardiovascular and renal prognosis in IgA nephropathy

Parameters

B

SE

Wald

df

Sig

Exp(B)

95% CI for Exp(B)

Lower Upper

Primary combined endpoint

 Age

1.419

0.345

4.567

1

0.092

2.136

1.468

2.340

 Gender

-0.981

0.418

5.516

1

0.019

0.375

0.165

0.850

 LVMI

0.036

0.006

34.638

1

< 0.001

1.037

1.025

1.050

 eGFR

-0.028

0.005

27.322

1

< 0.001

0.972

0.962

0.983

 Dyslipidemia

0.464

0.326

2.022

1

0.155

1.591

0.839

3.016

 Obesity

0.782

0.330

5.626

1

0.018

2.187

1.146

4.174

 Hypertension

1.845

0.726

6.452

1

0.011

6.325

1.524

26.253

 Diabetes

1.017

0.323

9.884

1

0.002

2.765

1.467

5.212

 Metabolic syndrome

1.214

0.324

14.015

1

 < 0.001

3.366

1.783

6.353

 ACEI/ARB therapy

-1.035

1.098

0.889

1

0.346

0.355

0.041

3.055

Renal endpoint

 Dyslipidemia

-0.801

0.508

2.488

1

0.115

0.449

0.166

1.214

 Obesity

0.077

0.458

0.028

1

0.866

1.080

0.440

2.651

 Hypertension

0.020

0.850

0.001

1

0.981

1.020

0.193

5.393

 Diabetes

0.544

0.437

1.548

1

0.213

1.722

0.731

4.054

 LVMI

0.024

0.008

9.444

1

0.002

1.024

1.009

1.040

 eGFR

-0.032

0.008

17.976

1

< 0.001

0.968

0.954

0.983

 ACEI/ARB

-0.790

1.120

0.498

1

0.481

0.454

0.050

4.077

Cardiovascular endpoint

 Dyslipidemia

0.328

0.693

0.225

1

0.636

1.389

0.357

5.399

 Obesity

-0.050

0.630

0.006

1

0.937

0.951

0.277

3.269

 Diabetes

1.491

0.631

5.592

1

0.018

4.443

1.291

15.296

 LVMI

0.046

0.014

11.539

1

0.001

1.047

1.020

1.075

 eGFR

0.008

0.012

0.483

1

0.487

1.009

0.985

1.033

  1. LVMI Left ventricle mass index, eGFR estimated glomerular filtration rate, HRR Heart rate recovery, SI Stiffness index, DVP Digital volume pulse, ACEI Angiotensin-converting enzyme-inhibitor; ARB Angiotensin II-receptor blocker