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Table 1 Baseline demographics, diagnoses, laboratory results, and medications data for normal and ESKD patient groups

From: Using CUSUM in real time to signal clinically relevant decreases in estimated glomerular filtration rate

 

Normal Group

(n = 85,699)

ESKD Group

(n = 5,410)

DEMOGRAPHICS

Mean Age in years**

64.5

57.9

Sex*

 Number Female (percent)

46,456 (54%)

2,354 (44%)

 Number Male (percent)

39,182 (46%)

3,056 (56%)

Race/Ethnicity*

 Number Black (percent)

5,826 (7%)

1,147 (21%)

 Number Native American (percent)

181 (0%)

110 (2%)

 Number Asian/Pacific Islander (percent)

1,062 (1%)

114 (2%)

 Number Hispanic (percent)

26 (0%)

55 (1%)

 Number Middle Eastern/Indian (percent)

490 (1%)

7 (0%)

 Number White (percent)

69,294 (81%)

3,589 (67%)

 Number Biracial (percent)

45 (0%)

7 (0%)

 Number Unknown (percent)

8,754 (10%)

381 (7%)

 Number with History of Smoking (percent)*

15,063 (18%)

2,423 (45%)

DIAGNOSES

Number with Hypertension (percent)*

46,502 (54%)

4,816 (89%)

Number with Diabetes Mellitus (percent)*

22,215 (26%)

3,403 (63%)

Number with Cardiovascular Disease (percent)*

 Coronary Artery Disease

12,812 (15%)

2,346 (43%)

 Cerebrovascular Disease (CVA, Stroke)

5,041 (6%)

764 (14%)

 Peripheral Vascular Disease

4,338 (5%)

1,168 (22%)

Number with History of Cancer (percent)*

10,294 (12%)

767 (14%)

Number with Hypercholesterolemia (percent)*

48,716 (57%)

3,404 (63%)

Number with History of Urinary Tract Abnormalities (percent)*

4633 (5%)

1512 (28%)

LABORATORY RESULTS

Urine Microalbumin/Creatinine (mg/g)*

 Number patients < 30 (percent)

12,755 (81.7%)

31 (25.6%)

 Number patients between 30 and 300 (percent)

2,593 (16.6%)

40 (33.1%)

 Number of patients >  = 300 (percent)

255 (1.7%)

50 (41.3%)

Urine Protein/Creatinine (g/g) (se)*

0.11 (0.010)

3.91 (1.247)

Hemoglobin A1c (g/dL) (se)*

5.3 (0.008)

7.2 (0.062)

Hemoglobin (g/dL) (se)*

13.4 (0.002)

10.9 (0.037)

Serum Calcium (mg/dL) (se)*

9.4 (0.001)

8.8 (0.014)

Serum Cholesterol (mg/dL) (se)*

182 (0.051)

159 (1.814)

Serum Albumin (g/dL) (se)*

4.1 (0.001)

3.2 (0.013)

Serum Phosphorus (mg/dL) (se)*

3.4 (0.001)

4.2 (0.034)

Number of patients Hepatitis C positive (percent)*

945 (1%)

237 (4%)

MEDICATION

Number with any NSAID Use (ibuprofen, naproxen, etc.) (percent)*

16,459 (19%)

2,518 (47%)

Number with any Proton Pump Inhibitor Use (omeprazole, etc.) (percent)*

9,689 (11%)

4,031 (75%)

Number with Bipolar Drug Use (Lithium) (percent)*

233 (0%)

28 (1%)

  1. se Standard error
  2. * Significant difference in means between normal and ESKD Groups based on chi-squared test (p < 0.05)
  3. ** Significant difference in means between normal and ESKD Groups based on t-test (p < 0.05)