Table 3 Primary and secondary outcomes according to MELD eras

Hospital length (days)

15 [11; 23]

13 [8; 22]

 < 0.01

ICU length (days)

3 [2; 8]

2 [1; 4]

 < 0.01

Retransplant during index hospitalization (%)

36 (8.8)

36 (7.7)

0.62

Acute liver rejection (%)

123 (30)

69 (15)

 < 0.01

Acute Kidney Injury (%)

342 (84)

364 (78)

0.04

  KDIGO 1

171 (41.9)

126 (27)

 < 0.01

  KDIGO 2

113 (27.7)

73 (15.7)

 < 0.01

  KDIGO 3

58 (14.2)

165 (35.4)

 < 0.01

Severe AKI (KDIGO 2 + 3) (%)

171 (41.8)

238 (58.2)

 < 0.01

Duration of AKI (days)

16 [10; 23]

6 [2; 23]

 < 0.01

Peak creatinine during AKI episode (mg/dL)

1.6 [1.1; 2.1]

1.9 [1.32; 2.69]

 < 0.01

Dialysis (%)

68 (17)

131 (28)

 < 0.01

  Continuous therapies (%)

39 (10)

68 (15)

0.03

  Intermittent therapies (%)

50 (12)

115 (28)

 < 0.01

Time of RRT dependence (days)

11.5 [3; 26.75]

17.5 [6; 43.75]

 < 0.01

Hospital mortality (%)

33 (8)

36 (8)

0.90

28 days mortality (%)

25 (6)

45 (10)

0.36

90 days mortality (%)

51 (13)

45 (10)

0.19

1-year mortality (%)

81 (20)

50 (11)

 < 0.01