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Table 1 Baseline characteristics of iMN patients between low-level and high-level group

From: Anti-phospholipase A2 receptor antibody levels at diagnosis predicts outcome of TAC-based treatment for idiopathic membranous nephropathy patients

Parameters

Low-level group(n = 52)

High-level group(n = 42)

P value

Level of anti-PLA2R Ab, RU/mL

72.20(39.59, 118.80)

374.31(262.50, 592.63)

 < 0.001

Gender, male/female

35/17

24/18

0.311

Age, year

55.27 ± 11.74

59.38 ± 13.05

0.112

Weight, kg

65.24 ± 9.06

63.52 ± 8.73

0.355

Systolic blood pressure, mmHg

131.27 ± 16.08

132.55 ± 19.71

0.730

Diastolic blood pressure, mmHg

83.08 ± 9.52

82.48 ± 8.41

0.750

Hemoglobin, g/L

128.07 ± 22.86

124.45 ± 14.61

0.355

Proteinuria, g/24 h

4.47 ± 1.64

5.02 ± 2.86

0.266

Total cholesterol, mmol/L

7.78 ± 2.86

8.71 ± 2.46

0.102

Triglyceride, mmol/L

2.39(1.65, 3.88)

2.28(1.58, 3.43)

0.533

Low density lipoprotein, mmol/L

4.70(3.47, 6.45)

6.18(4.53, 8.01)

0.010

Total protein, g/L

47.24 ± 7.53

45.39 ± 6.20

0.205

Serum albumin, g/L

23.43 ± 5.44

19.75 ± 4.31

0.005

Blood urea nitrogen, mmol/L

5.25(4.33, 6.38)

5.05(4.08, 6.35)

0.465

Serum creatinine, μmol/L

73.20(63.83, 86.08)

72.85(60.08, 91.48)

0.781

Trough blood concentration of TAC

5.82 ± 1.44

5.71 ± 1.51

0.733

eGFR, mL/min/1.73 m2

89.59 ± 17.41

85.75 ± 21.63

0.287

ACEI/ARB

48/52

40/42

0.878

  1. Bold indicate p value < 0.05
  2. Legend: anti-PLA2R Ab anti-phospholipase A2 receptor antibody, iMN idiopathic membranous nephropathy, eGFR estimated glomerular filtration rate, low-level group anti-PLA2R antibody titer ≤ 150 RU/ml, high-level group anti-PLA2R antibody titer > 150 RU/ml, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker