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Table 2 Characteristics at baseline and during treatment with sacubitril/valsartan

From: Cardio-renal benefits of sacubitril/valsartan in patients with advanced chronic kidney disease: experience in daily clinical practice

 

Baseline n = 22

First year n = 17

Second year n = 13

Serum creatinine, mg/dL

2.2 ± 0.6

1.9 ± 0.5

1.7 ± 0.4

eGFR, mL/min/1.73m2

29.4 ± 8.3

35.8 ± 9.4

39.8 ± 12.0

Potassium, mEq/L

4.61 ± 0.6

4.90 ± 0.6

4.87 ± 0.6

Urine protein:creatinine, mg/g

56.4 (26.3–427)

165 (100–313)

264 (51.3–1007.9)

Systolic blood pressure, mmHg

129.1 ± 20.2

124.2 ± 17.3

123.0 ± 18.1

Diastolic blood pressure, mmHg

70.2 ± 14.9

72.4 ± 11.0

70.4 ± 11.6

LVEF, %

36.4 ± 8.9

39.6 ± 10.2

38.8 ± 8.8

Visits to ED, number

1(0–2)

0 (0–0.3)

0 (0–0)

  1. Recorded at scheduled visits with the nephrologist. Values are all given as mean ± SD and median (IQR)
  2. ED Emergency Department, eGFR Estimated glomerular filtration rate calculated with CKD-EPI formula, LVEF Left ventricular ejection fraction