Table 9 Results of subgroup analysis and interaction analysis

Age(years)

0.6636

0.5920

  < 60(years)

218

0.859 (0.747, 0.988)

-0.308 (-0.881, 0.264)

  ≥ 60(years)

744

0.829 (0.751, 0.914)

-0.466 (-0.831, -0.102)

Gender

0.8543

0.6664

 Male

670

0.844 (0.766, 0.930)

-0.480 (-0.868, -0.092)

 Female

292

0.831 (0.722, 0.956)

-0.304 (-1.026, 0.417)

Urinary occult blood

0.1975

0.5015

 No

652

0.874 (0.786, 0.972)

-0.380 (-0.760, -0.001)

 Yes

310

0.788 (0.697, 0.892)

-0.566 (-1.080, -0.052)

BMI(kg/m2)

0.5280

0.1642

  < 23.5

492

0.825 (0.737, 0.924)

-0.715 (-1.168, -0.262)

  ≥ 23.5

470

0.866 (0.775, 0.968)

-0.304 (-0.752, 0.144)

SBP(mmHg)

0.0276

0.3823

  < 140

514

0.741 (0.651, 0.843)

-0.317 (-0.740, 0.107)

  ≥ 140

448

0.871 (0.791, 0.959)

-0.536 (-0.961, -0.111)

UPCR (g/gCr)

0.0145

0.2201

  < 0.5

458

0.683 (0.548, 0.851)

-0.217 (-0.742, 0.308)

  ≥ 0.5

504

0.903 (0.832, 0.981)

-0.637 (-1.075, -0.199)

Etiology of CKD

0.3714

0.9391

 Diabetic nephropathy

44

0.781 (0.692, 0.881)

-0.498 (-1.049, 0.053)

 Nephrosclerosis

85

0.943 (0.786, 1.130)

-0.391 (-0.846, 0.064)

 Glomerulonephritis

178

0.799 (0.605, 1.055)

-0.566 (-1.227, 0.096)

 Other

155

0.868 (0.613, 1.230)

-0.338 (-0.990, 0.314)

Use of RAAS inhibitor

0.9565

0.7207

 No

336

0.830 (0.712, 0.967)

-0.496 (-0.974, -0.018)

 Yes

626

0.834 (0.761, 0.913)

-0.404 (-0.789, -0.018)

Hypertension

0.0173

0.6052

 No

96

0.435 (0.257, 0.734)

-0.716 (-1.657, 0.225)

 Yes

866

0.842 (0.775, 0.915)

-0.457 (-0.823, -0.091)

History of CVD

0.0978

0.1901

 No

704

0.862 (0.787, 0.944)

-0.323 (-0.706, 0.059)

 Yes

258

0.755 (0.652, 0.874)

-0.694 (-1.212, -0.175)

Diabetes

0.7648

0.1948

 No

598

0.819 (0.728, 0.922)

-0.592 (-1.005, -0.179)

 Yes

364

0.837 (0.759, 0.923)

-0.208 (-0.697, 0.280)

Use of calcium channel blocker

0.2353

0.7644

 No

503

0.791 (0.698, 0.897)

-0.474 (-0.901, -0.047)

 Yes

459

0.869 (0.783, 0.965)

-0.398 (-0.821, 0.024)

Use of diuretics

0.0271

0.3428

 No

650

0.903 (0.811, 1.005)

-0.615 (-1.010, -0.220)

 Yes

312

0.761 (0.676, 0.856)

-0.329 (-0.854, 0.195)

ALB(g/dL)

0.8595

0.1032

 < 4

465

0.837 (0.768, 0.911)

-0.716 (-1.129, -0.303)

  ≥ 4

497

0.852 (0.711, 1.021)

-0.280 (-0.718, 0.159)