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Table 3 Distribution of rs662799 polymorphism in the APOA5 gene in ESKD patients with and without CVD

From: Apolipoprotein A5 gene polymorphism (rs662799) and cardiovascular disease in end-stage kidney disease patients

 

Genotypes

MAF

OR (95% CI)a

N

TT

TC

CC

 

C allele

CC genotypeb

TC genotypeb

ESKD CVD + 

552

423 (76.7)

105 (19)

24 (4.3)

0.14

2.41 (1.61–3.6)

3.13 (1.07–9.14)

2.38 (1.47–3.85)

      

p < 0.001

p = 0.036

p < 0.001

ESKD CVD-

248

221 (89.1)

23 (9.3)

4 (1.6)

0.06

ref

ref

ref

  1. Genotype distribution is shown as numbers (%)
  2. ESKD End-stage kidney disease, CVD Cardiovascular disease, APOA5 Apolipoprotein A5, MAF Minor allele frequency
  3. aAdjusted for age, sex, BMI, hypertension and diabetes
  4. bCalculated versus TT genotype