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Table 1 Pre-hospitalization, hospitalization, and post-hospitalization characteristics

From: Absence of long-term changes in urine biomarkers after AKI: findings from the CRIC study

Pre-Hospitalization
Characteristics
AKI Patients
(n = 198)
Non-AKI Patients
(n = 198)
P-Value
Age, yrs 67 [60–73] 67 [61–73] 0.48
Male 61% 64% 0.21
Race/Ethnicity
 Hispanic 10% 8% 0.67
 Non-Hispanic Black 47% 49%
 Non-Hispanic White 40% 40%
Diabetes mellitus 68% 68% 1.00
Estimated GFR, mL/min/1.73m2 47 [35–57] 46 [34–57] 0.10
Urine protein to creatinine ratio, g/g 0.24 [0.10–0.99] 0.26 [0.08–0.90] 0.48
Systolic blood pressure, mmHg 126 [113–142] 127 [114–139] 0.50
Days between pre-hospitalization measurement and admission 221 [138–291] 220 [123–283] 0.06
Hospitalization Characteristics
AKI Stagea
  Stage 1 66% N/A N/A
  Stage 2 28% N/A N/A
  Stage 3 7% N/A N/A
Cardiovascular Hospitalization 25% 27% 0.73
Infection-related Hospitalization 14% 8% 0.12
Post-Hospitalization Annual CRIC Visit Characteristics
 Estimated GFR, mL/min/1.73m2 42 [31–55] 46 [32–59]  < 0.01
 Urine protein to creatinine ratio, g/g 0.31 [0.11–1.06] 0.27 [0.10–0.91] 0.55
 Systolic blood pressure, mmHg 128 [113–143] 126 [115–138] 0.47
 Days between discharge and post-hospitalization measurement 161 [93–229] 160 [93–247] 0.20
 Days between pre-hospitalization and post-hospitalization measurements 369 [348–413] 365 [349–390]  < 0.01
  1. Median [IQR] for continuous variables or percentages for categorical variables. Missingness for pre-hospitalization variables was 9 patients for UPCR, 2 patients for SBP, and 1 patient for ACEi/ARB use. Missingness for post-hospitalization variables was 5 patients for eGFR, 23 patients for UPCR, 4 patients for SBP, and 3 patients for ACEi/ARB use.
  2. aPercentages do not sum to 100% due to rounding