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Table 1 Baseline characteristics of the development and validation cohorts (n,%)

From: Development of a risk prediction nomogram for sarcopenia in hemodialysis patients

Characteristics

Development cohort(N = 369)

Validation cohort(N = 246)

P value

Sociodemographic

Gender

 Female

138(37.40)

96(39.00)

0.684

 Male

231(62.60)

150(61.00)

 

Age (≥ 60 years)

176(47.70)

126(51.20)

0.392

Sarcopenia

 No

310(84.00)

203(82.50)

0.626

 Yes

59(16.00)

43(17.50)

 

Dialysis and clinical

Primary disease

 Chronic glomerulonephrit

259(70.20)

171(69.50)

0.110

 Diabetic nephropathy

67(18.20)

34(13.80)

 

 Other

43(11.70)

41(16.70)

 

 Duration of dialysis (> 60 months)

179(48.50)

128(52.00)

0.392

Biochemical

 Hemoglobin (< 110 g/L)

149(40.40)

97(39.40)

0.814

 Creatinine (< 884 μmol/L)

175(47.40)

108(43.90)

0.390

 Uric acid (> 420 μmol/L)

201(54.50)

147(59.80)

0.195

 Urea nitrogen (> 20 mmol/L)

107(29.00)

69(28.00)

0.799

 Kt/V (> 1.4)

248(67.20)

168(68.30)

0.778

 Serum Albumin(< 38 g/L)

107(29.00)

85(34.60)

0.145

 CRP (≥ 3 mg/L)

140(37.90)

101(41.10)

0.438

 Alkaline phosphatase (> 70.5U/L)

194(52.60)

137(55.70)

0.448

 Prealbumin (≤ 30 mg/dL)

140(37.90)

85(34.60)

0.393

 Ferritin (< 200 ng/mL)

251(68.00)

171(69.50)

0.696

 Potassium (> 5.5 mmol/L)

104(28.20)

51(20.70)

0.037

Phosphorus

 1.13–1.78 mmol/L

148(40.10)

91(36.99)

0.707

  > 1.78 mmol/L

208(56.40)

147(59.76)

 

  < 1.13 mmol/L

13(3.50)

8(3.25)

 

Calcium

 2.1–2.5 mmol/L

243(65.86)

146(59.30)

0.149

  > 2.5 mmol/L

63(17.07)

43(17.50)

 

  < 2.1 mmol/L

63(17.07)

57(23.20)

 

PTH

 150-300 pg/L

138(37.40)

84(34.14)

0.180

  > 300 pg/L

74(20.10)

65(26.43)

 

  < 150 pg/L

157(42.50)

97(39.43)

 

 Triglycerides (> 1.7 mmol/L)

175(47.40)

119(48.40)

0.818

 Cholesterol (< 2.59 mmol/L)

41(11.10)

36(14.60)

0.196

 HDL (< 1.03 mmol/L)

141(38.20)

93(37.80)

0.919

 LDL (> 3.37 mmol/L)

7(1.90)

7(2.80)

0.440

 VLDL (> 0.78 mmol/L)

171(46.30)

115(46.70)

0.921

Anthropometric indicators

 MAMC (< 22.64 cm)

151(40.90)

112(45.50)

0.258

Body mass index

  

0.978

 18.5–24.9 kg/m2

243(65.85)

164(66.67)

 

  > 25 kg/m2

55(14.91)

36(14.63)

 

  < 18.5 kg/m2

71(19.24)

46(18.70)

 

Psychological scores

 SAS (> 40)

23(6.20)

13(5.30)

0.624

 SDS (> 41)

41(11.10)

33(13.40)

0.390

  1. Kt/V Urea clearance index, CRP C-reactive protein, MAMC Mid-upper arm muscle circumference, SAS Self-rating anxiety scale, SDS Self-rating depression scale, PTH Parathyroid hormone, HDL High-density lipoprotein, LDL Low-density lipoprotein, VLDL Very low-density lipoprotein