Table1 Baseline characteristics of donors and recipients
ECD | SCD | P value | |
|---|---|---|---|
Donors | N = 52 | N = 159 | |
Age (years) | 54.31 ± 3.96 | 30.99 ± 11.84 | < 0.001 |
Sex, n (%) | 0.652 | ||
Male | 46 (88.5%) | 134 (84.3%) | |
Female | 6 (11.5%) | 25 (15.7%) | |
BMI (kg/m2) | 22.7 (21.2–24.2) | 22.0 (20.2–23.4) | 0.061 |
History of hypertension, n (%) | 38 (73.1%) | 20 (12.6%) | < 0.001 |
HBV infection, n (%) | 25 (15.7%) | 7 (13.5%) | 0.825 |
Cause of death, n (%) | 0.001 | ||
Cerebrovascular accident | 29 (55.8%) | 44 (27.7%) | |
Trauma | 19 (36.5%) | 99 (62.3%) | |
Other | 4 (7.7%) | 16 (10.1%) | |
Terminal Scr (μmol/L) | 134.0 (63.9–165.6) | 96.0 (67.0–142.8) | 0.160 |
Recipients | N = 104 | N = 311 | |
Age (years) | 40.04 ± 11.03 | 38.53 ± 10.09 | 0.197 |
Sex, n (%) | 0.715 | ||
Male | 73 (70.2%) | 210 (67.5%) | |
Female | 31 (29.8%) | 101 (32.5%) | |
BMI (kg/m2) | 21.2(19.2–23.0) | 21.1 (18.8–23.0) | 0.382 |
Cause of renal failure, n(%) | 0.446 | ||
Glomerulonephropathy | 80 (76.8%) | 219 (70.4%) | |
IgA nephropathy | 8 (7.7%) | 38 (12.2%) | |
Diabetic nephropathy | 8 (7.7%) | 21 (6.8%) | |
Others | 8 (7.7%) | 33 (10.6%) | |
History of hypertension, n (%) | 59 (56.7%) | 158 (50.8%) | 0.309 |
History of diabetes, n (%) | 25 (24.0%) | 53 (17.0%) | 0.146 |
Dialysis duration (months) | 24.0 (12.0–39.8) | 18.0 (10.0–36.0) | 0.058 |
HLA mismatches | 0.135 | ||
0–3 | 37 (35.6%) | 85 (27.3%) | |
4–6 | 67 (64.6%) | 226 (72.7%) | |
Cold ischemia time (h) | 8.94 ± 2.70 | 8.0 ± 2.69 | 0.974 |
Negative PRA, n (%) | 98 (94.2%) | 296 (95.2%) | 0.792 |
Remuzzi score | 3.07 ± 1.14 | 2.82 ± 1.26 | 0.076 |
Process | |||
Cardiac arrest, n (%) | 0.395 | ||
Controlled | 46 (88.5%) | 147 (92.5%) | |
Uncontrolled | 6 (11.5%) | 12 (7.5%) | |
Warm ischemia time (min) | 0.631 | ||
≤ 15 min | 26 (50.0%) | 72 (45.3%) | |
> 15 min | 26 (50.0%) | 87 (54.7%) | |
Induction therapy, n (%) | 0.603 | ||
ATG | 25 (8.0%) | 10(9.6%) | |
Basiliximab | 263(84.6%) | 89(85.6%) | |
Others | 23(7.4%) | 5(4.8%) | |