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Table 7 Clinical profiles of HD patients who died or survived 0 to 14, 15 to 30, and > 30 days after COVID-19 presentation in North America

From: Predictors of shorter- and longer-term mortality after COVID-19 presentation among dialysis patients: parallel use of machine learning models in Latin and North American countries

 

North America

 

Most Recent value 0 to 14 days prior to COVID symptoms

Most Recent value > 14 days prior to COVID symptoms

Delta

Mean ± SD or N (%)

Mean ± SD or N (%)

Mean ± SD or N (%)

Parameter

Died 0–14 days

Died 15–30 days

Died > 30 days

Survived

Died 0–14 days

Died 15–30 days

Died > 30 days

Survived

Died 0–14 days

Died 15–30 days

Died > 30 days

Survived

Laboratories

 Albumin

3.47 ± 0.55

3.55 ± 0.52

3.42 ± 0.52

3.70 ± 0.44

3.58 ± 0.51

3.62 ± 0.48

3.48 ± 0.50

3.75 ± 0.42

-0.07 ± 0.31

-0.06 ± 0.31

-0.05 ± 0.31

-0.04 ± 0.28

 Calcium

8.70 ± 0.74

8.74 ± 0.72

8.70 ± 0.80

8.72 ± 0.73

8.82 ± 0.66

8.79 ± 0.65

8.78 ± 0.72

8.84 ± 0.68

-0.11 ± 0.58

-0.06 ± 0.60

-0.07 ± 0.64

-0.12 ± 0.60

 Corrected calcium

9.14 ± 0.68

9.10 ± 0.70

9.16 ± 0.74

8.97 ± 0.69

9.16 ± 0.66

9.10 ± 0.65

9.19 ± 0.68

9.04 ± 0.68

-0.04 ± 0.55

-0.01 ± 0.61

-0.03 ± 0.62

-0.08 ± 0.57

 Creatinine

7.48 ± 2.89

7.74 ± 2.80

7.07 ± 2.63

8.40 ± 3.24

7.51 ± 2.72

7.77 ± 2.82

7.16 ± 2.59

8.35 ± 3.06

0.12 ± 1.46

0.12 ± 1.46

0.00 ± 1.47

0.22 ± 1.56

 Ferritin

956.16 ± 436.70

985.37 ± 441.67

952.81 ± 433.73

963.78 ± 433.18

988.30 ± 411.87

1006.37 ± 418.79

976.56 ± 423.73

955.72 ± 418.56

41.40 ± 339.42

23.93 ± 363.71

10.77 ± 339.47

62.77 ± 346.94

 Hgb

10.40 ± 1.35

10.48 ± 1.44

10.25 ± 1.44

10.56 ± 1.34

10.46 ± 1.31

10.59 ± 1.39

10.27 ± 1.39

10.65 ± 1.29

-0.03 ± 0.92

-0.09 ± 0.91

-0.03 ± 1.01

-0.06 ± 0.90

 Lymphocytes

16.76 ± 9.28

17.08 ± 8.03

17.32 ± 8.78

19.26 ± 8.26

18.23 ± 8.81

18.52 ± 7.47

17.91 ± 8.20

20.21 ± 7.99

-1.60 ± 6.90

-1.32 ± 6.66

-0.31 ± 6.73

-1.07 ± 6.50

 Neutrophils

70.27 ± 10.96

69.99 ± 10.10

69.52 ± 10.70

67.35 ± 9.97

68.41 ± 10.34

68.05 ± 9.10

68.55 ± 10.05

66.17 ± 9.58

1.83 ± 8.92

1.72 ± 8.44

0.76 ± 8.90

1.25 ± 8.53

 Phosphate

5.07 ± 1.73

5.07 ± 1.59

5.14 ± 1.80

5.37 ± 1.72

5.03 ± 1.68

5.20 ± 1.74

5.15 ± 1.70

5.38 ± 1.68

-0.06 ± 1.43

-0.16 ± 1.50

-0.09 ± 1.63

-0.07 ± 1.49

 Platelets

195.83 ± 90.83

187.57 ± 78.68

190.68 ± 88.67

191.99 ± 78.34

196.95 ± 87.36

192.81 ± 78.38

195.43 ± 88.79

199.80 ± 76.65

-6.70 ± 60.57

-2.55 ± 56.37

-5.11 ± 61.36

-9.73 ± 55.50

 Parathyroid hormone

392.91 ± 308.39

408.23 ± 329.49

403.69 ± 336.24

456.62 ± 325.89

384.75 ± 279.71

403.60 ± 293.19

392.67 ± 297.63

427.66 ± 304.70

-22.71 ± 224.93

-23.40 ± 241.05

-9.38 ± 242.53

1.38 ± 232.09

 Transferrin saturation

29.39 ± 14.71

30.12 ± 13.42

29.57 ± 14.14

29.59 ± 14.19

31.79 ± 13.93

32.86 ± 13.87

31.29 ± 14.26

32.92 ± 14.07

-1.90 ± 15.18

-2.42 ± 14.41

-1.91 ± 16.79

-2.99 ± 16.35

 White blood cell count

7.17 ± 3.22

6.88 ± 2.99

6.95 ± 2.75

6.57 ± 2.66

7.33 ± 3.42

7.04 ± 2.80

7.13 ± 3.54

6.92 ± 2.54

-0.06 ± 2.54

-0.17 ± 2.91

-0.26 ± 2.39

-0.41 ± 2.34

Vital signs

 Pre-HD SBP

138.0 ± 28.1

141.9 ± 27.4

139.7 ± 27.8

145.8 ± 27.2

72.4 ± 15.5

73.0 ± 14.2

72.4 ± 15.4

77.0 ± 15.7

-4.5 ± 27.6

-3.1 ± 27.3

-3.0 ± 27.5

-2.7 ± 27.2

 Post-HD SBP

140.6 ± 27.1

140.7 ± 26.3

140.2 ± 25.8

144.5 ± 26.0

70.5 ± 13.8

71.1 ± 13.2

70.8 ± 14.6

73.9 ± 14.2

3.3 ± 26.4

2.0 ± 26.6

1.4 ± 26.1

3.8 ± 25.7

 Pre-HD DBP

70.5 ± 15.5

72.1 ± 15.4

71.3 ± 15.6

75.7 ± 16.0

142.4 ± 27.4

145.2 ± 26.7

142.8 ± 27.0

148.6 ± 26.4

-2.0 ± 16.5

-0.9 ± 15.4

-1.0 ± 16.1

-1.4 ± 15.9

 Post-HD DBP

72.1 ± 15.2

71.5 ± 14.6

71.2 ± 14.8

75.1 ± 14.9

137.3 ± 24.6

138.7 ± 24.0

138.7 ± 24.7

140.8 ± 24.6

1.6 ± 15.9

0.4 ± 14.8

0.4 ± 15.5

1.20 ± 15.1

 Pre-HD pulse

81.08 ± 14.96

80.80 ± 14.63

78.98 ± 14.55

80.52 ± 13.73

77.13 ± 13.13

77.93 ± 13.61

77.75 ± 14.10

78.34 ± 12.86

3.93 ± 13.76

2.88 ± 13.26

1.44 ± 12.84

2.18 ± 12.13

 Post-HD pulse

81.83 ± 15.00

81.01 ± 15.07

79.01 ± 14.98

79.66 ± 13.95

76.32 ± 12.85

76.08 ± 12.67

76.18 ± 13.50

75.88 ± 12.32

5.49 ± 15.37

4.91 ± 14.91

3.06 ± 14.54

3.83 ± 13.42

 Pre-HD temperature

36.58 ± 0.58

36.56 ± 0.53

36.55 ± 0.52

36.59 ± 0.55

36.38 ± 0.43

36.40 ± 0.42

36.41 ± 0.43

36.41 ± 0.43

0.20 ± 0.66

0.16 ± 0.61

0.14 ± 0.60

0.19 ± 0.62

 Post-HD temperature

36.60 ± 0.62

36.56 ± 0.58

36.52 ± 0.53

36.62 ± 0.59

36.39 ± 0.40

36.38 ± 0.39

36.39 ± 0.40

36.42 ± 0.39

0.22 ± 0.68

0.19 ± 0.65

0.14 ± 0.60

0.20 ± 0.65

Weights

 Pre-HD weight

84.39 ± 25.27

84.41 ± 24.45

80.85 ± 23.86

86.15 ± 24.73

85.19 ± 25.32

85.00 ± 24.09

81.56 ± 23.90

87.02 ± 24.81

-0.92 ± 2.79

-0.78 ± 2.78

-0.72 ± 2.74

-0.88 ± 2.73

 Post-HD weight

82.82 ± 24.81

82.70 ± 23.96

79.11 ± 23.40

84.32 ± 24.31

83.09 ± 24.82

82.92 ± 23.51

79.55 ± 23.38

84.74 ± 24.31

-0.39 ± 3.07

-0.41 ± 2.39

-0.44 ± 2.42

-0.44 ± 2.13

 IDWG

1.79 ± 1.47

1.95 ± 1.67

1.96 ± 1.61

1.96 ± 1.56

2.19 ± 1.62

2.28 ± 1.52

2.23 ± 1.62

2.37 ± 1.48

-0.42 ± 1.75

-0.35 ± 1.90

-0.28 ± 1.94

-0.43 ± 1.75

 Dry weight

82.70 ± 24.69

82.53 ± 23.77

78.86 ± 23.20

84.34 ± 24.24

82.86 ± 24.60

82.57 ± 23.24

79.19 ± 23.30

84.43 ± 24.23

-0.28 ± 1.88

-0.29 ± 1.98

-0.34 ± 1.94

-0.15 ± 1.77

  1. P-values for univariate comparison of died versus survived (reference) are shown with bold font representing p < 0.05. Albumin and hemoglobin (Hgb) are reported in units of g/dL. Calcium, corrected calcium, creatinine, and phosphate are reported in units of mg/dL. Ferritin is reported in unit of ng/mL. Parathyroid hormone is reported in the unit of pg/mL. Lymphocytes, neutrophils, and transferrin saturation (TSAT) are reported in unit of percent (%). Platelets and white blood cell counts are reported in unit of 10^3/µL. Systolic/diastolic blood pressures (SBP/DBP) are reported in units of mmHg. Pulse is reported in unit of BPM. Temperature is reported in unit of Celsius. Weights are reported in unit of Kg