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Table 4 Comparison of two groups of IV iron interventions

From: Routine laboratory testing in hemodialysis: how frequently is it needed?

 

With ≤ 4 interventions per year and less for Iron

n = 110

With > 4 interventions per year for Iron

n = 100

p-value

Age, median (IQR)

68 (61, 78)

74 (65, 79.8)

0.021*

Sex, M/F (%)

72/38 (65.5/34.5)

59/41 (59/41)

0.335**

Dialysis vintage (months), median (IQR)

36 (25, 67)

32.5 (19, 64.3)

0.234*

Diabetes, n(%)

53 (48.2)

46 (46)

0.752**

Hypertension, n(%)

106 (96.4)

95 (95)

0.739****

Smoking status, n(%)

37 (33.6)

43 (43)

0.163**

CAD, n(%)

50 (45.5)

32 (32)

0.052**

Cancer, n(%)

18 (16.4)

10 (10)

0.175**

Monthly dose of ESA, median (IQR)

21,500 (14958.3, 44750.3)

22,000 (14658.8, 37,875)

0.612*

Monthly dose of IV iron, mean ± SD

1.1 ± 1.04

1.2 ± 1.1

0.874***

Yearly number of interventions in ESA prescription

Mean ± SD

3.8 ± 2.6

5.5 ± 2.3

< 0.001***

Yearly number of interventions in IV iron prescription

Mean ± SD

2.2 ± 1.3

6.5 ± 1.4

< 0.001***

Hemoglobin over one year, median (IQR)

11.3 (10.8, 11.9)

11.1 (10.8, 11.6)

0.039*

Ferritin over one year, Mean ± SD

508.2 ± 287.5

561.9 ± 220.1

0.134***

TSAT over one year, median (IQR)

0.25 (0.21, 0.30)

0.26 (0.21, 0.32)

0.423*

URR over one year, mean ± SD

0.75 ± 0.05

0.76 ± 0.05

0.316***

Serum potassium over one year, median (IQR)

5.2 (4.8, 5.6)

5.1 (4.6, 5.4)

0.120*

  1. *Mann Whitney test, **Chi Square test, ***Independent t-test ****Fischer’s Exact test; P-value < 0.05 is statistically significant