Table 2 Primary Analysis – Key Lab Values
ERC, (n = 174) | AVD, (n = 55) | NVD, (n = 147) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lab Value | Pre | Post | ∆ | MeanFU | MedFU | Pre | Post | ∆ | MeanFU | MedFU | Pre | Post | ∆ | MeanFU | MedFU |
25D, ng/mL* Mean (SE) | 20.3a (0.7) | 44.0 (1.7) | 23.7aa,bb,cc (1.6) | 24.6 | 19.9 | 23.5 (1.0) | 29.0 (1.2) | 5.5cc (1.3) | 21.3 | 18.1 | 18.8aa (0.6) | 28.5 (1.6) | 9.7cc (1.5) | 21.1 | 17.6 |
PTH, pg/mL* Mean (SE) | 181.4bb (7.4) | 147.4 (7.1) | −34.1bb,cc (6.6) | 23.4 | 18.8 | 156.9 (9.7) | 149.9 (11.1) | −7.0 (9.8) | 21.6 | 18.1 | 134.8 (6.8) | 144.4 (9.5) | 9.6 (6.0) | 20.7 | 17.4 |
Ca, mg/dL Mean (SE) | 9.2b (0.1) | 9.3 (0.1) | 0.1 (0.1) | 27.8 | 22.2 | 9.1 (0.1) | 9.3 (0.1) | 0.2cc (0.1) | 21.4 | 18.1 | 9.3 (0.1) | 9.3 (0.1) | 0.0 (0.1) | 20.4 | 16.1 |
P, mg/dL Mean (SE) | 3.8 (0.1) | 3.9 (0.1) | 0.1 (0.1) | 28.8 | 22.1 | 3.8 (0.2) | 3.9 (0.2) | 0.1 (0.1) | 24.5 | 18.6 | 3.7 (0.1) | 3.8 (0.1) | 0.1 (0.1) | 20.5 | 15.9 |
ALP, IU/L Mean (SE) | 96.9 (3.6) | 95.3 (3.8) | −2.1 (1.9) | 28.4 | 21.6 | 82.1 (7.4) | 79.8 (6.5) | −2.3 (2.7) | 21.3 | 18.6 | 97.0 (3.4) | 99.8 (4.0) | 2.7 (2.4) | 18.3 | 14.7 |
eGFR Mean (SE) | 31.1b (1.1) | 28.0 (0.9) | −3.1cc (0.7) | 28.1 | 22.2 | 30.3b (1.4) | 28.7 (1.6) | −1.6c (0.6) | 21.4 | 18.1 | 35.7 (1.0) | 34.5 (1.0) | −1.2c (0.6) | 20.0 | 16.0 |