Table 1 Demographic characteristics of patients
From: Clinical manifestations and pathological correlation of immunoglobulin A nephropathy in children
Clinical characteristic at diagnosis | Total n = 47 |
• Male n (%) | 28(59.6) |
• Mean age at diagnosis (year) (min, max) | 13.0 ± 3.4(6,18.6) |
• Mean weight (Kg) (min, max) | 48.0 ± 20.2(17,113.3) |
• Mean height (cm) (min, max) | 146.9 ± 17.3(117.5,179) |
• Mean arterial pressure (mmHg) (median, IQR) | 88.6(82.3,103.0) |
• Serum creatinine (mg/dL) (median, IQR) | 0.6(0.5,1.5) |
• Estimate glomerular filtration rate (mL/min/1.73m2) (median, IQR) | 97.8(46.9,112.8) |
• Urine protein creatinine ratio (mg/mg) (median, IQR) | 1.74(0.7,6.4) |
Clinical manifestations at diagnosis | n(%) |
• Microscopic hematuria | 30(63.8) |
• Significant proteinuria | 22(46.8) |
• Nephrotic range proteinuria | 22(46.8) |
• Hypertension | 21(44.6) |
• Edema | 20(42.5) |
• AKI/RPGN | 14(29.7) |
• Gross hematuria | 10(21.2) |
Treatment after diagnosis | n(%) |
• Prednisolone | 36(76.6) |
• Angiotensin converting enzyme inhibitors | 30(63.8) |
• Cyclophosphamide | 21(44.7) |
• Pulse methylprednisolone | 12(25.5) |
• Mycophenolate mofetil | 7(14.9) |
• Calcineurin inhibitors | 1(2.1) |